Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 47 studies | 59% ± 26% | |
pericyte | 35 studies | 48% ± 24% | |
endothelial cell | 31 studies | 34% ± 15% | |
smooth muscle cell | 25 studies | 42% ± 20% | |
endothelial cell of lymphatic vessel | 18 studies | 47% ± 20% | |
connective tissue cell | 18 studies | 56% ± 19% | |
macrophage | 16 studies | 34% ± 17% | |
mesothelial cell | 14 studies | 60% ± 22% | |
capillary endothelial cell | 11 studies | 31% ± 8% | |
myofibroblast cell | 11 studies | 49% ± 26% | |
endothelial cell of vascular tree | 11 studies | 34% ± 11% | |
endothelial cell of artery | 10 studies | 35% ± 8% | |
vein endothelial cell | 9 studies | 32% ± 10% | |
type I pneumocyte | 8 studies | 36% ± 16% | |
astrocyte | 7 studies | 31% ± 14% | |
alveolar macrophage | 6 studies | 52% ± 19% | |
monocyte | 6 studies | 29% ± 8% | |
hepatocyte | 6 studies | 68% ± 28% | |
type II pneumocyte | 6 studies | 23% ± 8% | |
epithelial cell | 6 studies | 47% ± 24% | |
plasmacytoid dendritic cell | 5 studies | 27% ± 8% | |
adventitial cell | 5 studies | 73% ± 27% | |
glial cell | 5 studies | 24% ± 6% | |
cholangiocyte | 4 studies | 46% ± 21% | |
abnormal cell | 4 studies | 39% ± 12% | |
kidney loop of Henle epithelial cell | 4 studies | 39% ± 14% | |
ciliated cell | 4 studies | 35% ± 13% | |
myeloid cell | 4 studies | 26% ± 9% | |
endothelial cell of sinusoid | 4 studies | 30% ± 7% | |
Schwann cell | 4 studies | 44% ± 21% | |
hematopoietic stem cell | 4 studies | 30% ± 9% | |
hepatic stellate cell | 3 studies | 42% ± 16% | |
T cell | 3 studies | 22% ± 3% | |
glomerular endothelial cell | 3 studies | 45% ± 6% | |
progenitor cell | 3 studies | 21% ± 3% | |
basal cell | 3 studies | 30% ± 7% | |
myoepithelial cell | 3 studies | 55% ± 11% | |
pancreatic ductal cell | 3 studies | 76% ± 11% | |
secretory cell | 3 studies | 28% ± 7% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 34% ± 15% | |
non-classical monocyte | 3 studies | 20% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 11 studies | 27% ± 10% | |
liver | 5 studies | 36% ± 17% | |
kidney | 5 studies | 21% ± 5% | |
uterus | 5 studies | 33% ± 10% | |
breast | 4 studies | 26% ± 6% | |
brain | 3 studies | 18% ± 3% | |
ovary | 3 studies | 32% ± 17% | |
heart | 3 studies | 16% ± 1% | |
adipose | 3 studies | 22% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 119317.47 | 226 / 226 | 100% | 823.44 | 405 / 406 |
ovary | 100% | 73503.49 | 180 / 180 | 99% | 259.26 | 427 / 430 |
breast | 100% | 64401.74 | 458 / 459 | 93% | 138.91 | 1038 / 1118 |
lung | 100% | 66488.58 | 577 / 578 | 91% | 124.80 | 1050 / 1155 |
prostate | 94% | 29187.57 | 231 / 245 | 86% | 82.51 | 430 / 502 |
thymus | 99% | 30692.24 | 645 / 653 | 81% | 82.09 | 491 / 605 |
uterus | 99% | 55670.22 | 169 / 170 | 77% | 101.56 | 352 / 459 |
kidney | 90% | 26550.80 | 80 / 89 | 86% | 253.68 | 771 / 901 |
bladder | 100% | 46522.43 | 21 / 21 | 64% | 82.61 | 324 / 504 |
pancreas | 71% | 11867.52 | 233 / 328 | 92% | 253.53 | 163 / 178 |
skin | 83% | 20832.28 | 1500 / 1809 | 77% | 131.23 | 365 / 472 |
esophagus | 85% | 31969.82 | 1230 / 1445 | 69% | 77.50 | 127 / 183 |
intestine | 92% | 26149.95 | 891 / 966 | 57% | 64.65 | 298 / 527 |
stomach | 71% | 24169.70 | 255 / 359 | 68% | 88.73 | 194 / 286 |
adrenal gland | 67% | 10303.56 | 174 / 258 | 41% | 29.73 | 94 / 230 |
adipose | 100% | 76391.76 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 82683.88 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 218.28 | 75 / 80 |
lymph node | 0% | 0 | 0 / 0 | 93% | 157.90 | 27 / 29 |
spleen | 92% | 20371.85 | 222 / 241 | 0% | 0 | 0 / 0 |
heart | 84% | 22009.75 | 727 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 76% | 68.69 | 34 / 45 |
brain | 3% | 381.78 | 67 / 2642 | 40% | 50.19 | 282 / 705 |
muscle | 30% | 4178.74 | 239 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 2% | 321.37 | 19 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001869 | Biological process | negative regulation of complement activation, lectin pathway |
GO_0006958 | Biological process | complement activation, classical pathway |
GO_0007596 | Biological process | blood coagulation |
GO_0008015 | Biological process | blood circulation |
GO_0010951 | Biological process | negative regulation of endopeptidase activity |
GO_0045087 | Biological process | innate immune response |
GO_0042730 | Biological process | fibrinolysis |
GO_0005615 | Cellular component | extracellular space |
GO_0072562 | Cellular component | blood microparticle |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0070062 | Cellular component | extracellular exosome |
GO_0031093 | Cellular component | platelet alpha granule lumen |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0004867 | Molecular function | serine-type endopeptidase inhibitor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SERPING1 |
Protein name | Serpin family G member 1 (Serpin peptidase inhibitor clade G member 1 isoform 2) (Serpin peptidase inhibitor clade G member 1 isoform 3) Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2 Serpin family G member 1 Serine/cysteine proteinase inhibitor clade G member 1 splice variant 3 Serpin peptidase inhibitor clade G member 1 Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1) Serpin peptidase inhibitor clade G member 1 isoform 4 Epididymis tissue protein Li 173 (Serpin peptidase inhibitor clade G member 1 isoform 1) |
Synonyms | C1IN C1NH |
Description | FUNCTION: Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. . |
Accessions | ENST00000457869.1 A0A7I2V2X2 ENST00000340687.10 ENST00000531133.5 ENST00000378324.6 [P05155-2] ENST00000531605.2 ENST00000678592.1 ENST00000378323.8 [P05155-3] Q5UGI6 ENST00000278407.9 [P05155-1] A0A7I2V4I9 ENST00000619430.2 ENST00000531797.5 ENST00000528996.2 H9KV48 ENST00000403558.1 E9PK97 ENST00000676670.1 [P05155-1] A0A7I2V2D2 ENST00000677625.1 ENST00000405496.5 ENST00000677915.1 ENST00000678533.1 A0A348GSH7 A0A087WUD9 A0A0S2Z333 C9JZJ9 E9KL26 A0A7I2V5R3 H0YCA1 ENST00000677624.1 Q5UGI5 P05155 E9PGN7 B5MCB9 |