SERPING1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001869Biological processnegative regulation of complement activation, lectin pathway
GO_0006958Biological processcomplement activation, classical pathway
GO_0007596Biological processblood coagulation
GO_0008015Biological processblood circulation
GO_0010951Biological processnegative regulation of endopeptidase activity
GO_0045087Biological processinnate immune response
GO_0042730Biological processfibrinolysis
GO_0005615Cellular componentextracellular space
GO_0072562Cellular componentblood microparticle
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0070062Cellular componentextracellular exosome
GO_0031093Cellular componentplatelet alpha granule lumen
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSERPING1
Protein nameSerpin family G member 1 (Serpin peptidase inhibitor clade G member 1 isoform 2) (Serpin peptidase inhibitor clade G member 1 isoform 3)
Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2
Serpin family G member 1
Serine/cysteine proteinase inhibitor clade G member 1 splice variant 3
Serpin peptidase inhibitor clade G member 1
Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1)
Serpin peptidase inhibitor clade G member 1 isoform 4
Epididymis tissue protein Li 173 (Serpin peptidase inhibitor clade G member 1 isoform 1)
SynonymsC1IN
C1NH
DescriptionFUNCTION: Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. .

AccessionsENST00000457869.1
A0A7I2V2X2
ENST00000340687.10
ENST00000531133.5
ENST00000378324.6 [P05155-2]
ENST00000531605.2
ENST00000678592.1
ENST00000378323.8 [P05155-3]
Q5UGI6
ENST00000278407.9 [P05155-1]
A0A7I2V4I9
ENST00000619430.2
ENST00000531797.5
ENST00000528996.2
H9KV48
ENST00000403558.1
E9PK97
ENST00000676670.1 [P05155-1]
A0A7I2V2D2
ENST00000677625.1
ENST00000405496.5
ENST00000677915.1
ENST00000678533.1
A0A348GSH7
A0A087WUD9
A0A0S2Z333
C9JZJ9
E9KL26
A0A7I2V5R3
H0YCA1
ENST00000677624.1
Q5UGI5
P05155
E9PGN7
B5MCB9