Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 15 studies | 22% ± 8% | |
| non-classical monocyte | 15 studies | 25% ± 7% | |
| monocyte | 12 studies | 24% ± 8% | |
| dendritic cell | 7 studies | 22% ± 8% | |
| neutrophil | 6 studies | 27% ± 5% | |
| macrophage | 6 studies | 20% ± 4% | |
| plasmacytoid dendritic cell | 5 studies | 24% ± 9% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 4 studies | 19% ± 3% | |
| conventional dendritic cell | 4 studies | 26% ± 7% | |
| naive B cell | 3 studies | 20% ± 5% | |
| B cell | 3 studies | 19% ± 3% | |
| T follicular helper cell | 3 studies | 19% ± 2% | |
| regulatory T cell | 3 studies | 22% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| peripheral blood | 4 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 1576.10 | 577 / 578 | 90% | 13.26 | 1041 / 1155 |
| esophagus | 99% | 1149.30 | 1436 / 1445 | 87% | 13.96 | 160 / 183 |
| breast | 100% | 1923.92 | 459 / 459 | 85% | 9.37 | 948 / 1118 |
| bladder | 95% | 902.90 | 20 / 21 | 87% | 15.05 | 437 / 504 |
| ovary | 84% | 622.53 | 151 / 180 | 92% | 17.76 | 396 / 430 |
| stomach | 92% | 1019.64 | 329 / 359 | 76% | 7.82 | 218 / 286 |
| uterus | 84% | 592.72 | 143 / 170 | 83% | 13.71 | 379 / 459 |
| skin | 92% | 886.77 | 1665 / 1809 | 74% | 16.91 | 347 / 472 |
| intestine | 97% | 1151.16 | 940 / 966 | 67% | 6.13 | 351 / 527 |
| thymus | 97% | 949.34 | 635 / 653 | 37% | 3.29 | 225 / 605 |
| pancreas | 39% | 184.47 | 127 / 328 | 91% | 12.80 | 162 / 178 |
| kidney | 74% | 800.81 | 66 / 89 | 37% | 2.22 | 332 / 901 |
| prostate | 89% | 622.19 | 219 / 245 | 21% | 1.51 | 104 / 502 |
| spleen | 100% | 5840.07 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 2293.85 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 11716.48 | 928 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 16.84 | 28 / 29 |
| heart | 94% | 890.98 | 806 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 15.42 | 41 / 45 |
| blood vessel | 76% | 659.11 | 1020 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 34% | 181.49 | 87 / 258 | 22% | 1.67 | 50 / 230 |
| brain | 22% | 139.97 | 592 / 2642 | 25% | 2.12 | 175 / 705 |
| liver | 20% | 103.94 | 46 / 226 | 23% | 1.77 | 95 / 406 |
| muscle | 33% | 163.79 | 264 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.77 | 3 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0051028 | Biological process | mRNA transport |
| GO_0045087 | Biological process | innate immune response |
| GO_0009615 | Biological process | response to virus |
| GO_0051607 | Biological process | defense response to virus |
| GO_0035455 | Biological process | response to interferon-alpha |
| GO_0046822 | Biological process | regulation of nucleocytoplasmic transport |
| GO_0015031 | Biological process | protein transport |
| GO_0051726 | Biological process | regulation of cell cycle |
| GO_0006952 | Biological process | defense response |
| GO_0005643 | Cellular component | nuclear pore |
| GO_0005874 | Cellular component | microtubule |
| GO_0016020 | Cellular component | membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005525 | Molecular function | GTP binding |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | MX2 |
| Protein name | Interferon-induced GTP-binding protein Mx2 MX2 Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (Myxovirus resistance protein 2) (p78-related protein) MX dynamin like GTPase 2 |
| Synonyms | |
| Description | FUNCTION: Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression. . |
| Accessions | C9J9T4 A0A7P0Z4E8 ENST00000418103.2 [P20592-2] C9JEL4 ENST00000481838.5 C9JS04 Q75MY8 C9JZQ9 ENST00000330714.8 [P20592-1] ENST00000416447.1 ENST00000435611 ENST00000436410.5 ENST00000435611.6 [P20592-1] Q75MY7 P20592 ENST00000418103 ENST00000680862.1 [P20592-1] |