Insufficient scRNA-seq data for expression of USP29 at single-cell level.
Insufficient scRNA-seq data for expression of USP29 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 8% | 2.20 | 203 / 2642 | 1% | 0.01 | 4 / 705 |
| adipose | 8% | 0.94 | 99 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
| breast | 2% | 0.43 | 11 / 459 | 0% | 0.00 | 2 / 1118 |
| esophagus | 1% | 0.11 | 11 / 1445 | 1% | 0.02 | 2 / 183 |
| prostate | 2% | 0.46 | 4 / 245 | 0% | 0 | 0 / 502 |
| intestine | 1% | 0.09 | 12 / 966 | 0% | 0.01 | 1 / 527 |
| heart | 1% | 0.10 | 12 / 861 | 0% | 0 | 0 / 0 |
| spleen | 1% | 0.13 | 3 / 241 | 0% | 0 | 0 / 0 |
| thymus | 1% | 0.17 | 8 / 653 | 0% | 0 | 0 / 605 |
| lung | 1% | 0.07 | 5 / 578 | 0% | 0.00 | 4 / 1155 |
| blood vessel | 1% | 0.08 | 16 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 1% | 0.07 | 3 / 258 | 0% | 0 | 0 / 230 |
| pancreas | 1% | 0.06 | 3 / 328 | 0% | 0 | 0 / 178 |
| liver | 1% | 0.09 | 2 / 226 | 0% | 0 | 0 / 406 |
| muscle | 1% | 0.13 | 7 / 803 | 0% | 0 | 0 / 0 |
| skin | 1% | 0.10 | 15 / 1809 | 0% | 0 | 0 / 472 |
| peripheral blood | 1% | 0.05 | 6 / 929 | 0% | 0 | 0 / 0 |
| stomach | 1% | 0.04 | 2 / 359 | 0% | 0 | 0 / 286 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 1 / 901 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0 | 0 / 504 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| uterus | 0% | 0 | 0 / 170 | 0% | 0 | 0 / 459 |
| GO_0051607 | Biological process | defense response to virus |
| GO_0071108 | Biological process | protein K48-linked deubiquitination |
| GO_0050821 | Biological process | protein stabilization |
| GO_0006508 | Biological process | proteolysis |
| GO_0060340 | Biological process | positive regulation of type I interferon-mediated signaling pathway |
| GO_0000082 | Biological process | G1/S transition of mitotic cell cycle |
| GO_0045087 | Biological process | innate immune response |
| GO_0016579 | Biological process | protein deubiquitination |
| GO_0005575 | Cellular component | cellular_component |
| GO_0005829 | Cellular component | cytosol |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0004197 | Molecular function | cysteine-type endopeptidase activity |
| GO_0004843 | Molecular function | cysteine-type deubiquitinase activity |
| Gene name | USP29 |
| Protein name | Ubiquitin specific peptidase 29 Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) ubiquitinyl hydrolase 1 (EC 3.4.19.12) Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.4.19.12) (Deubiquitinating enzyme 29) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) |
| Synonyms | |
| Description | FUNCTION: Deubiquitinase involved in innate antiviral immunity by mediating 'Lys-48'-linked deubiquitination of CGAS, thereby promoting its stabilization. . FUNCTION: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. . |
| Accessions | M0R2Y1 ENST00000598197.1 A1L447 ENST00000600020.5 M0QZL0 Q9HBJ7 ENST00000600940.1 ENST00000254181.9 |