N4BP3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of N4BP3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of N4BP3 at tissue level.

III. Associated gene sets

GO_0007399Biological processnervous system development
GO_0045087Biological processinnate immune response
GO_0030424Cellular componentaxon
GO_0031410Cellular componentcytoplasmic vesicle
GO_0030425Cellular componentdendrite
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameN4BP3
Protein nameNEDD4-binding protein 3 (N4BP3)
SynonymsKIAA0341
DescriptionFUNCTION: Plays a positive role in the antiviral innate immune signaling pathway. Mechanistically, interacts with MAVS and functions as a positive regulator to promote 'Lys-63'-linked polyubiquitination of MAVS and thus strengthens the interaction between MAVS and TRAF2 . Also plays a role in axon and dendrite arborization during cranial nerve development. May also be important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage (By similarity). .

AccessionsENST00000274605.6
O15049