OASL | OmnibusX

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	7 studies	25% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	19% ± 4%	Explore
natural killer cell	6 studies	21% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	23% ± 8%	Explore
alveolar macrophage	4 studies	19% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	16% ± 1%	Explore
T cell	3 studies	32% ± 10%	Explore
macrophage	3 studies	26% ± 5%	Explore
classical monocyte	3 studies	22% ± 3%	Explore
non-classical monocyte	3 studies	22% ± 1%	Explore
gamma-delta T cell	3 studies	17% ± 2%	Explore
mature NK T cell	3 studies	18% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of OASL at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	98%	583.51	222 / 226	82%	17.92	332 / 406
lung	100%	762.96	577 / 578	80%	14.44	919 / 1155
stomach	84%	739.75	300 / 359	86%	17.31	247 / 286
breast	86%	240.53	397 / 459	83%	21.38	926 / 1118
intestine	63%	225.28	612 / 966	86%	16.04	453 / 527
bladder	67%	85.90	14 / 21	82%	20.73	412 / 504
esophagus	55%	161.74	791 / 1445	90%	29.98	164 / 183
kidney	71%	246.78	63 / 89	62%	6.66	556 / 901
thymus	72%	113.54	470 / 653	39%	4.18	234 / 605
uterus	24%	33.40	41 / 170	83%	29.86	380 / 459
skin	40%	53.56	725 / 1809	63%	10.53	296 / 472
spleen	100%	428.74	241 / 241	0%	0	0 / 0
peripheral blood	100%	1771.98	927 / 929	0%	0	0 / 0
pancreas	8%	7.93	27 / 328	90%	29.76	160 / 178
ovary	18%	15.92	33 / 180	79%	18.11	341 / 430
tonsil	0%	0	0 / 0	96%	45.96	43 / 45
adipose	89%	242.95	1076 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	83%	16.98	24 / 29
brain	34%	66.67	900 / 2642	27%	4.34	192 / 705
adrenal gland	26%	54.45	66 / 258	20%	2.20	46 / 230
prostate	31%	36.05	75 / 245	10%	1.73	50 / 502
blood vessel	32%	53.68	433 / 1335	0%	0	0 / 0
heart	26%	34.75	226 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	20%	2.70	16 / 80
muscle	7%	9.99	58 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0009615	Biological process	response to virus
GO_0051607	Biological process	defense response to virus
GO_0060700	Biological process	regulation of ribonuclease activity
GO_0045071	Biological process	negative regulation of viral genome replication
GO_1900246	Biological process	positive regulation of RIG-I signaling pathway
GO_0070106	Biological process	interleukin-27-mediated signaling pathway
GO_0045087	Biological process	innate immune response
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0003725	Molecular function	double-stranded RNA binding
GO_0001730	Molecular function	2'-5'-oligoadenylate synthetase activity
GO_0003677	Molecular function	DNA binding
GO_0046966	Molecular function	nuclear thyroid hormone receptor binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

Gene name	OASL
Protein name	2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL) 2'-5'-oligoadenylate synthetase like 2'-5'-oligoadenylate synthase-like protein
Synonyms	TRIP14
Description	FUNCTION: Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. .
Accessions	ENST00000620239.5 [Q15646-3] ENST00000257570.10 [Q15646-1] ENST00000543677.2 [Q15646-2] ENST00000679358.1 A0A7P0TB39 ENST00000679655.1 H0YGP3 ENST00000680620.1 A0A7P0T9H8 ENST00000543677 ENST00000680485.1 ENST00000681590.1 A0A7P0TBF4 Q15646 ENST00000339275.10 [Q15646-2]

OASL report