KCNJ16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034765Biological processregulation of monoatomic ion transmembrane transport
GO_0006813Biological processpotassium ion transport
GO_1990573Biological processpotassium ion import across plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0008076Cellular componentvoltage-gated potassium channel complex
GO_0016323Cellular componentbasolateral plasma membrane
GO_0005242Molecular functioninward rectifier potassium channel activity

IV. Literature review

[source]
Gene nameKCNJ16
Protein namePotassium inwardly-rectifying channel, subfamily J, member 16
Potassium inwardly rectifying channel subfamily J member 16
Inward rectifier potassium channel 16 (Inward rectifier K(+) channel Kir5.1) (Potassium channel, inwardly rectifying subfamily J member 16)
Synonyms
DescriptionFUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules . .

AccessionsQ8N538
ENST00000615244.4
K7EKJ4
ENST00000587698.5
ENST00000392670.5
Q9NPI9
ENST00000587892.1
K7ELL5
ENST00000283936.5
ENST00000589377.1
ENST00000392671.6
ENST00000591891.5