AQP2 | OmnibusX

Name	Number of supported studies	Average coverage
renal principal cell	5 studies	58% ± 22%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of AQP2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	98%	351.73	253 / 258	47%	76.58	107 / 230
kidney	100%	36873.29	89 / 89	12%	4.20	108 / 901
prostate	68%	195.41	167 / 245	2%	0.20	11 / 502
pancreas	47%	17.09	154 / 328	19%	0.34	33 / 178
skin	55%	15.97	986 / 1809	1%	0.01	3 / 472
thymus	47%	13.36	307 / 653	2%	0.03	13 / 605
stomach	42%	6.72	151 / 359	7%	0.40	19 / 286
heart	48%	83.20	411 / 861	0%	0	0 / 0
lung	39%	8.67	228 / 578	5%	1.11	63 / 1155
bladder	43%	9.33	9 / 21	1%	0.02	6 / 504
breast	38%	7.72	174 / 459	2%	0.07	18 / 1118
blood vessel	39%	36.25	525 / 1335	0%	0	0 / 0
uterus	27%	6.96	46 / 170	10%	0.25	45 / 459
ovary	14%	3.14	25 / 180	13%	0.26	57 / 430
esophagus	13%	1.68	184 / 1445	13%	1.14	23 / 183
adipose	17%	3.47	203 / 1204	0%	0	0 / 0
intestine	4%	0.47	41 / 966	5%	0.38	25 / 527
brain	7%	0.70	193 / 2642	0%	0.00	1 / 705
muscle	3%	0.32	28 / 803	0%	0	0 / 0
liver	3%	0.23	7 / 226	0%	0.00	1 / 406
spleen	3%	0.46	8 / 241	0%	0	0 / 0
peripheral blood	2%	0.20	21 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071288	Biological process	cellular response to mercury ion
GO_0015793	Biological process	glycerol transmembrane transport
GO_0003091	Biological process	renal water homeostasis
GO_0072205	Biological process	metanephric collecting duct development
GO_0003097	Biological process	renal water transport
GO_0006833	Biological process	water transport
GO_0071280	Biological process	cellular response to copper ion
GO_0007015	Biological process	actin filament organization
GO_0042631	Biological process	cellular response to water deprivation
GO_0051289	Biological process	protein homotetramerization
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0016020	Cellular component	membrane
GO_0055037	Cellular component	recycling endosome
GO_0070062	Cellular component	extracellular exosome
GO_0005794	Cellular component	Golgi apparatus
GO_0098576	Cellular component	lumenal side of membrane
GO_0030658	Cellular component	transport vesicle membrane
GO_0016323	Cellular component	basolateral plasma membrane
GO_0015250	Molecular function	water channel activity
GO_0015168	Molecular function	glycerol transmembrane transporter activity
GO_0005372	Molecular function	water transmembrane transporter activity
GO_0005515	Molecular function	protein binding

Gene name	AQP2
Protein name	Aquaporin-2 (AQP-2) (ADH water channel) (Aquaporin-CD) (AQP-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct) Aquaporin-2 (ADH water channel) (Aquaporin-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct) Aquaporin-2 mutant
Synonyms
Description	FUNCTION: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient . Plays an essential role in renal water homeostasis . .
Accessions	Q6FGT3 ENST00000199280.4 ENST00000551526.5 F8W0S2 ENST00000550862.1 P41181 Q8NHX2 F8VPL3

AQP2 report