SIM1 | OmnibusX

Name	Number of supported studies	Average coverage
kidney distal convoluted tubule epithelial cell	3 studies	28% ± 5%	Explore
renal principal cell	3 studies	23% ± 6%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SIM1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	1431.85	89 / 89	71%	5.91	641 / 901
pancreas	98%	305.11	323 / 328	31%	1.22	55 / 178
breast	81%	237.00	373 / 459	16%	1.09	176 / 1118
skin	76%	437.38	1374 / 1809	1%	0.04	3 / 472
adipose	52%	420.68	632 / 1204	0%	0	0 / 0
muscle	46%	105.45	366 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	18%	0.94	8 / 45
liver	5%	4.79	12 / 226	11%	0.40	43 / 406
lymph node	0%	0	0 / 0	7%	0.30	2 / 29
brain	6%	31.33	160 / 2642	1%	0.03	4 / 705
uterus	0%	0	0 / 170	3%	0.13	15 / 459
intestine	1%	1.48	13 / 966	2%	0.08	9 / 527
ovary	0%	0	0 / 180	3%	0.06	12 / 430
lung	0%	0	0 / 578	3%	0.11	29 / 1155
stomach	1%	0.78	3 / 359	1%	0.02	3 / 286
prostate	1%	4.45	3 / 245	1%	0.01	3 / 502
esophagus	0%	0.08	1 / 1445	2%	0.04	3 / 183
bladder	0%	0	0 / 21	1%	0.09	7 / 504
blood vessel	1%	2.33	15 / 1335	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	0%	0.01	1 / 230
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
thymus	0%	0	0 / 653	0%	0	0 / 605
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001657	Biological process	ureteric bud development
GO_0007399	Biological process	nervous system development
GO_0030154	Biological process	cell differentiation
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003677	Molecular function	DNA binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0000977	Molecular function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515	Molecular function	protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific

Gene name	SIM1
Protein name	Single-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14) Alternative protein SIM1
Synonyms	BHLHE14
Description	FUNCTION: Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
Accessions	L0R542 P81133 ENST00000369208.8 ENST00000262901.4

SIM1 report