SCNN1G | OmnibusX

Name	Number of supported studies	Average coverage
renal principal cell	4 studies	51% ± 4%	Explore
type I pneumocyte	3 studies	16% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SCNN1G at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	96%	904.43	629 / 653	89%	20.89	537 / 605
lung	97%	1275.38	559 / 578	59%	9.36	685 / 1155
prostate	86%	2454.07	211 / 245	70%	11.82	349 / 502
kidney	99%	3644.24	88 / 89	11%	6.73	97 / 901
ureter	0%	0	0 / 0	100%	88.37	1 / 1
breast	51%	287.93	232 / 459	47%	8.55	527 / 1118
pancreas	67%	306.76	220 / 328	29%	8.57	52 / 178
bladder	38%	191.10	8 / 21	56%	30.68	282 / 504
skin	71%	1027.99	1291 / 1809	2%	0.17	8 / 472
tonsil	0%	0	0 / 0	69%	12.97	31 / 45
stomach	65%	1262.22	232 / 359	4%	0.29	11 / 286
esophagus	39%	541.35	559 / 1445	30%	2.84	54 / 183
uterus	10%	106.27	17 / 170	47%	10.73	216 / 459
intestine	29%	799.19	280 / 966	8%	0.90	42 / 527
brain	18%	207.17	482 / 2642	4%	0.28	29 / 705
ovary	2%	7.92	3 / 180	10%	2.25	44 / 430
adipose	12%	51.32	143 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.23	1 / 29
adrenal gland	1%	2.70	2 / 258	3%	0.34	6 / 230
blood vessel	1%	3.09	10 / 1335	0%	0	0 / 0
peripheral blood	1%	1.12	5 / 929	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0.46	2 / 406
muscle	0%	0.61	2 / 803	0%	0	0 / 0
heart	0%	2.20	1 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0

GO_0008217	Biological process	regulation of blood pressure
GO_0055078	Biological process	sodium ion homeostasis
GO_0050891	Biological process	multicellular organismal-level water homeostasis
GO_0006883	Biological process	intracellular sodium ion homeostasis
GO_0050914	Biological process	sensory perception of salty taste
GO_0071468	Biological process	cellular response to acidic pH
GO_0050915	Biological process	sensory perception of sour taste
GO_1904117	Biological process	cellular response to vasopressin
GO_1904045	Biological process	cellular response to aldosterone
GO_0006814	Biological process	sodium ion transport
GO_0098719	Biological process	sodium ion import across plasma membrane
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0016324	Cellular component	apical plasma membrane
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0034706	Cellular component	sodium channel complex
GO_0005272	Molecular function	sodium channel activity
GO_0005216	Molecular function	monoatomic ion channel activity
GO_0015280	Molecular function	ligand-gated sodium channel activity
GO_0050699	Molecular function	WW domain binding
GO_0005515	Molecular function	protein binding

Gene name	SCNN1G
Protein name	Amiloride-sensitive epithelial sodium channel gamma subunit Amiloride-sensitive sodium channel subunit gamma (Epithelial Na(+) channel subunit gamma) (ENaCG) (Gamma-ENaC) (Gamma-NaCH) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) Amiloride-sensitive sodium channel subunit gamma (Epithelial Na(+) channel subunit gamma) (Gamma-NaCH) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG)
Synonyms	hCG_1685795
Description	FUNCTION: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. .
Accessions	Q6LCK5 Q6LCK6 Q6LA62 ENST00000300061.3 A5X2V1 Q6LCK3 Q6LCK4 P51170

SCNN1G report