Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 12 studies | 30% ± 14% | |
astrocyte | 11 studies | 33% ± 16% | |
glutamatergic neuron | 10 studies | 51% ± 24% | |
GABAergic neuron | 10 studies | 46% ± 26% | |
oligodendrocyte precursor cell | 10 studies | 35% ± 16% | |
adipocyte | 9 studies | 22% ± 5% | |
fibroblast | 8 studies | 24% ± 10% | |
interneuron | 6 studies | 53% ± 26% | |
oligodendrocyte | 6 studies | 26% ± 11% | |
type I pneumocyte | 6 studies | 32% ± 9% | |
endothelial cell of lymphatic vessel | 5 studies | 25% ± 8% | |
smooth muscle cell | 5 studies | 21% ± 1% | |
neuron | 4 studies | 33% ± 8% | |
granule cell | 4 studies | 29% ± 7% | |
microglial cell | 4 studies | 20% ± 5% | |
retinal ganglion cell | 4 studies | 23% ± 8% | |
epithelial cell | 4 studies | 34% ± 18% | |
pericyte | 4 studies | 22% ± 8% | |
GABAergic interneuron | 3 studies | 40% ± 3% | |
cardiac muscle cell | 3 studies | 17% ± 2% | |
Mueller cell | 3 studies | 20% ± 1% | |
amacrine cell | 3 studies | 24% ± 0% | |
glycinergic amacrine cell | 3 studies | 22% ± 4% | |
ependymal cell | 3 studies | 31% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1664.36 | 245 / 245 | 99% | 15.36 | 499 / 502 |
brain | 100% | 2912.63 | 2638 / 2642 | 99% | 17.55 | 699 / 705 |
esophagus | 100% | 2071.23 | 1445 / 1445 | 99% | 12.63 | 181 / 183 |
thymus | 100% | 2218.76 | 653 / 653 | 98% | 14.33 | 591 / 605 |
pancreas | 99% | 1329.21 | 326 / 328 | 97% | 8.68 | 173 / 178 |
ovary | 100% | 2495.85 | 180 / 180 | 96% | 11.10 | 414 / 430 |
bladder | 100% | 2013.62 | 21 / 21 | 96% | 9.54 | 485 / 504 |
stomach | 100% | 1305.33 | 359 / 359 | 95% | 8.51 | 271 / 286 |
intestine | 100% | 1553.43 | 966 / 966 | 95% | 7.48 | 499 / 527 |
lung | 99% | 1563.12 | 572 / 578 | 95% | 10.08 | 1102 / 1155 |
breast | 100% | 1896.95 | 459 / 459 | 94% | 13.57 | 1053 / 1118 |
uterus | 100% | 2453.08 | 170 / 170 | 93% | 10.03 | 428 / 459 |
skin | 100% | 2345.63 | 1809 / 1809 | 93% | 11.98 | 440 / 472 |
kidney | 100% | 1463.01 | 89 / 89 | 92% | 10.18 | 826 / 901 |
adrenal gland | 100% | 1683.73 | 257 / 258 | 86% | 6.98 | 197 / 230 |
liver | 89% | 624.06 | 201 / 226 | 79% | 5.36 | 321 / 406 |
adipose | 100% | 1837.62 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1737.81 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 3184.76 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.07 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 96% | 10.06 | 43 / 45 |
heart | 92% | 1062.23 | 792 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 9.29 | 72 / 80 |
spleen | 87% | 530.17 | 209 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.37 | 3 / 29 |
peripheral blood | 6% | 39.35 | 60 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016197 | Biological process | endosomal transport |
GO_0006897 | Biological process | endocytosis |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0031901 | Cellular component | early endosome membrane |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005829 | Cellular component | cytosol |
GO_0005769 | Cellular component | early endosome |
GO_0005545 | Molecular function | 1-phosphatidylinositol binding |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | ZFYVE9 |
Protein name | Alternative protein ZFYVE9 Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation) |
Synonyms | MADHIP SMADIP SARA |
Description | FUNCTION: Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. . |
Accessions | L8E993 O95405 ENST00000371591.2 [O95405-1] L8ECB6 ENST00000357206.6 [O95405-2] ENST00000287727.8 [O95405-1] |