SMAD9 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071773Biological processcellular response to BMP stimulus
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0030509Biological processBMP signaling pathway
GO_0060395Biological processSMAD protein signal transduction
GO_0030154Biological processcell differentiation
GO_0009653Biological processanatomical structure morphogenesis
GO_0007179Biological processtransforming growth factor beta receptor signaling pathway
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0071141Cellular componentSMAD protein complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0071144Cellular componentheteromeric SMAD protein complex
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0046872Molecular functionmetal ion binding
GO_0070411Molecular functionI-SMAD binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSMAD9
Protein nameSMAD family member 9
Mothers against decapentaplegic homolog 9 (MAD homolog 9) (Mothers against DPP homolog 9) (Madh6) (SMAD family member 9) (SMAD 9) (Smad9)
SynonymsMADH6
SMAD8
MADH9
DescriptionFUNCTION: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).

AccessionsENST00000350148.10 [O15198-2]
A0A7I2R5A4
O15198
ENST00000399275.7
ENST00000379826.5 [O15198-1]