FSHB | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of FSHB at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	25%	5.52	658 / 2642	0%	0.00	2 / 705
liver	21%	2.85	48 / 226	0%	0	0 / 406
adrenal gland	21%	7.22	54 / 258	0%	0	0 / 230
spleen	17%	1.28	40 / 241	0%	0	0 / 0
kidney	16%	0.98	14 / 89	0%	0	0 / 901
prostate	14%	1.38	35 / 245	0%	0	0 / 502
stomach	12%	10.48	44 / 359	1%	0.01	2 / 286
pancreas	13%	0.90	42 / 328	0%	0	0 / 178
ovary	12%	0.92	22 / 180	0%	0	0 / 430
thymus	11%	0.96	69 / 653	1%	0.03	5 / 605
uterus	11%	0.68	19 / 170	0%	0	0 / 459
esophagus	11%	2.81	152 / 1445	0%	0	0 / 183
adipose	10%	1.45	119 / 1204	0%	0	0 / 0
lung	8%	0.56	49 / 578	0%	0.03	4 / 1155
intestine	9%	0.78	85 / 966	0%	0	0 / 527
heart	8%	0.63	67 / 861	0%	0	0 / 0
skin	6%	4.24	112 / 1809	0%	0	0 / 472
breast	6%	0.36	28 / 459	0%	0.00	1 / 1118
blood vessel	6%	2.38	80 / 1335	0%	0	0 / 0
peripheral blood	6%	0.47	53 / 929	0%	0	0 / 0
muscle	5%	0.36	44 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bladder	0%	0	0 / 21	0%	0	0 / 504
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007283	Biological process	spermatogenesis
GO_0010469	Biological process	regulation of signaling receptor activity
GO_0010628	Biological process	positive regulation of gene expression
GO_0042699	Biological process	follicle-stimulating hormone signaling pathway
GO_0010893	Biological process	positive regulation of steroid biosynthetic process
GO_0007565	Biological process	female pregnancy
GO_0045670	Biological process	regulation of osteoclast differentiation
GO_0006701	Biological process	progesterone biosynthetic process
GO_0060011	Biological process	Sertoli cell proliferation
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0030335	Biological process	positive regulation of cell migration
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0007179	Biological process	transforming growth factor beta receptor signaling pathway
GO_0045780	Biological process	positive regulation of bone resorption
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0007292	Biological process	female gamete generation
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0016914	Cellular component	follicle-stimulating hormone complex
GO_0005737	Cellular component	cytoplasm
GO_0016913	Molecular function	follicle-stimulating hormone activity
GO_0005515	Molecular function	protein binding

Gene name	FSHB
Protein name	Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (Follitropin beta chain) Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (FSH-B) (FSH-beta) (Follitropin beta chain) Follicle-stimulating hormone beta subunit
Synonyms
Description	FUNCTION: Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways . Follitropin is involved in follicle development and spermatogenesis in reproductive organs . .
Accessions	ENST00000254122.8 ENST00000533718.2 Q1W658 P01225 A0A0F7RQE8 ENST00000417547.1 Q27RP3

FSHB report