Name | Number of supported studies | Average coverage | |
---|---|---|---|
retina horizontal cell | 7 studies | 79% ± 13% | |
glutamatergic neuron | 3 studies | 22% ± 5% | |
pancreatic ductal cell | 3 studies | 41% ± 27% | |
neuron | 3 studies | 40% ± 17% |
Insufficient scRNA-seq data for expression of ONECUT2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 2700.47 | 226 / 226 | 97% | 13.20 | 392 / 406 |
pancreas | 100% | 1188.68 | 328 / 328 | 89% | 13.46 | 159 / 178 |
adrenal gland | 75% | 105.38 | 193 / 258 | 49% | 1.69 | 112 / 230 |
brain | 76% | 778.92 | 2009 / 2642 | 34% | 0.69 | 240 / 705 |
stomach | 9% | 7.03 | 32 / 359 | 59% | 9.03 | 170 / 286 |
prostate | 13% | 12.95 | 33 / 245 | 51% | 1.97 | 255 / 502 |
esophagus | 3% | 4.53 | 38 / 1445 | 60% | 11.33 | 109 / 183 |
intestine | 6% | 17.16 | 62 / 966 | 49% | 4.21 | 256 / 527 |
uterus | 7% | 5.39 | 12 / 170 | 31% | 1.94 | 142 / 459 |
ovary | 25% | 19.06 | 45 / 180 | 12% | 0.88 | 52 / 430 |
tonsil | 0% | 0 | 0 / 0 | 36% | 0.60 | 16 / 45 |
bladder | 5% | 2.71 | 1 / 21 | 25% | 1.44 | 127 / 504 |
kidney | 15% | 22.27 | 13 / 89 | 14% | 0.56 | 128 / 901 |
lung | 1% | 0.55 | 4 / 578 | 26% | 2.55 | 302 / 1155 |
breast | 1% | 1.09 | 5 / 459 | 20% | 0.77 | 229 / 1118 |
skin | 2% | 1.09 | 29 / 1809 | 17% | 0.54 | 81 / 472 |
thymus | 18% | 13.33 | 116 / 653 | 0% | 0.02 | 3 / 605 |
muscle | 3% | 3.55 | 27 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 4.55 | 25 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 3% | 0.06 | 2 / 80 |
adipose | 1% | 1.41 | 13 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 0.62 | 12 / 1335 | 0% | 0 | 0 / 0 |
spleen | 1% | 2.91 | 2 / 241 | 0% | 0 | 0 / 0 |
heart | 0% | 0.11 | 1 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060271 | Biological process | cilium assembly |
GO_1905319 | Biological process | mesenchymal stem cell migration |
GO_0030512 | Biological process | negative regulation of transforming growth factor beta receptor signaling pathway |
GO_1905322 | Biological process | positive regulation of mesenchymal stem cell migration |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0001889 | Biological process | liver development |
GO_0001952 | Biological process | regulation of cell-matrix adhesion |
GO_0045165 | Biological process | cell fate commitment |
GO_0048935 | Biological process | peripheral nervous system neuron development |
GO_0031018 | Biological process | endocrine pancreas development |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0002064 | Biological process | epithelial cell development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
Gene name | ONECUT2 |
Protein name | One cut domain family member 2 (Hepatocyte nuclear factor 6-beta) (HNF-6-beta) (One cut homeobox 2) (Transcription factor ONECUT-2) (OC-2) |
Synonyms | HNF6B |
Description | FUNCTION: Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B. |
Accessions | O95948 ENST00000491143.3 |