ONECUT2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ONECUT2 at tissue level.

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_1905319Biological processmesenchymal stem cell migration
GO_0030512Biological processnegative regulation of transforming growth factor beta receptor signaling pathway
GO_1905322Biological processpositive regulation of mesenchymal stem cell migration
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0009887Biological processanimal organ morphogenesis
GO_0001889Biological processliver development
GO_0001952Biological processregulation of cell-matrix adhesion
GO_0045165Biological processcell fate commitment
GO_0048935Biological processperipheral nervous system neuron development
GO_0031018Biological processendocrine pancreas development
GO_0007179Biological processtransforming growth factor beta receptor signaling pathway
GO_0002064Biological processepithelial cell development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0015629Cellular componentactin cytoskeleton
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding

IV. Literature review

[source]
Gene nameONECUT2
Protein nameOne cut domain family member 2 (Hepatocyte nuclear factor 6-beta) (HNF-6-beta) (One cut homeobox 2) (Transcription factor ONECUT-2) (OC-2)
SynonymsHNF6B
DescriptionFUNCTION: Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.

AccessionsO95948
ENST00000491143.3