PXN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034614Biological processcellular response to reactive oxygen species
GO_0051496Biological processpositive regulation of stress fiber assembly
GO_0007165Biological processsignal transduction
GO_0060396Biological processgrowth hormone receptor signaling pathway
GO_0007155Biological processcell adhesion
GO_0034446Biological processsubstrate adhesion-dependent cell spreading
GO_0043542Biological processendothelial cell migration
GO_0007172Biological processsignal complex assembly
GO_0007179Biological processtransforming growth factor beta receptor signaling pathway
GO_0016477Biological processcell migration
GO_0005886Cellular componentplasma membrane
GO_0005925Cellular componentfocal adhesion
GO_0005911Cellular componentcell-cell junction
GO_0001725Cellular componentstress fiber
GO_0005829Cellular componentcytosol
GO_0005938Cellular componentcell cortex
GO_0030027Cellular componentlamellipodium
GO_0005875Cellular componentmicrotubule associated complex
GO_0019903Molecular functionprotein phosphatase binding
GO_0008013Molecular functionbeta-catenin binding
GO_0017166Molecular functionvinculin binding
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding
GO_0038191Molecular functionneuropilin binding

IV. Literature review

[source]
Gene namePXN
Protein nameHCG1778014 (PXN protein)
PXN protein
Paxillin
SynonymshCG_1778014
hCG_27772
DescriptionFUNCTION: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Recruits other proteins such as TRIM15 to focal adhesion. .

AccessionsA0A1B0GTU4
F8W0K8
ENST00000543331.1
P49023
ENST00000458477.6 [P49023-4]
ENST00000547983.5
ENST00000546532.5
ENST00000424649.6 [P49023-2]
ENST00000228307.11 [P49023-1]
F8W0G0
F8W1E0
ENST00000552550.5
ENST00000548912.5
ENST00000637624.1
F5H836
Q9BTK0
ENST00000536957.5
ENST00000267257.11 [P49023-3]
A0A140VJQ8
A0A1B0GWE7
ENST00000637617.2
F5GZ78
A0A1B0GU60
ENST00000323871.9
F8VZ39
Q7Z7K5
A0A1B0GV30
ENST00000637386.1