Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 27 studies | 25% ± 8% | |
astrocyte | 13 studies | 26% ± 9% | |
endothelial cell | 11 studies | 25% ± 7% | |
smooth muscle cell | 9 studies | 22% ± 5% | |
myofibroblast cell | 9 studies | 27% ± 7% | |
basal cell | 7 studies | 21% ± 7% | |
oligodendrocyte precursor cell | 7 studies | 24% ± 6% | |
type I pneumocyte | 6 studies | 26% ± 9% | |
epithelial cell | 6 studies | 30% ± 9% | |
abnormal cell | 5 studies | 27% ± 7% | |
pericyte | 5 studies | 17% ± 1% | |
GABAergic neuron | 4 studies | 27% ± 8% | |
glutamatergic neuron | 4 studies | 30% ± 13% | |
connective tissue cell | 4 studies | 31% ± 11% | |
ciliated cell | 4 studies | 22% ± 5% | |
club cell | 3 studies | 26% ± 7% | |
muscle cell | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 26724.71 | 180 / 180 | 100% | 90.54 | 429 / 430 |
thymus | 100% | 23404.82 | 653 / 653 | 100% | 153.49 | 602 / 605 |
prostate | 100% | 20940.41 | 245 / 245 | 98% | 48.43 | 494 / 502 |
pancreas | 99% | 6930.54 | 326 / 328 | 96% | 65.41 | 171 / 178 |
brain | 95% | 7406.63 | 2515 / 2642 | 100% | 94.78 | 705 / 705 |
breast | 100% | 13950.64 | 458 / 459 | 95% | 48.02 | 1063 / 1118 |
lung | 100% | 13882.82 | 577 / 578 | 95% | 48.17 | 1093 / 1155 |
adrenal gland | 100% | 14067.98 | 257 / 258 | 94% | 44.64 | 217 / 230 |
skin | 97% | 8290.30 | 1761 / 1809 | 93% | 57.45 | 441 / 472 |
kidney | 99% | 10894.73 | 88 / 89 | 90% | 49.02 | 814 / 901 |
esophagus | 96% | 12944.54 | 1382 / 1445 | 92% | 40.77 | 168 / 183 |
uterus | 100% | 26174.07 | 170 / 170 | 82% | 37.31 | 377 / 459 |
bladder | 100% | 15869.81 | 21 / 21 | 80% | 26.51 | 405 / 504 |
stomach | 98% | 9839.42 | 352 / 359 | 78% | 30.38 | 222 / 286 |
intestine | 98% | 14489.60 | 946 / 966 | 69% | 22.83 | 364 / 527 |
liver | 85% | 4743.28 | 191 / 226 | 76% | 28.81 | 310 / 406 |
blood vessel | 100% | 38542.71 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 9723.95 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 25.52 | 1 / 1 |
adipose | 100% | 12556.76 | 1201 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 39.30 | 79 / 80 |
heart | 99% | 12932.15 | 849 / 861 | 0% | 0 | 0 / 0 |
muscle | 93% | 5361.31 | 749 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 73% | 18.19 | 33 / 45 |
lymph node | 0% | 0 | 0 / 0 | 66% | 13.47 | 19 / 29 |
peripheral blood | 17% | 768.43 | 162 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0002062 | Biological process | chondrocyte differentiation |
GO_0060430 | Biological process | lung saccule development |
GO_0046849 | Biological process | bone remodeling |
GO_0060349 | Biological process | bone morphogenesis |
GO_1902462 | Biological process | positive regulation of mesenchymal stem cell proliferation |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0030502 | Biological process | negative regulation of bone mineralization |
GO_0030282 | Biological process | bone mineralization |
GO_0045780 | Biological process | positive regulation of bone resorption |
GO_2000741 | Biological process | positive regulation of mesenchymal stem cell differentiation |
GO_0032331 | Biological process | negative regulation of chondrocyte differentiation |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0050431 | Molecular function | transforming growth factor beta binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | LTBP3 |
Protein name | Latent-transforming growth factor beta-binding protein 3 (LTBP-3) LTBP3 protein (Latent transforming growth factor beta binding protein 3, isoform CRA_c) Latent transforming growth factor beta binding protein 3 |
Synonyms | hCG_1812642 |
Description | FUNCTION: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. . |
Accessions | ENST00000526825.6 ENST00000530866.6 ENST00000322147.8 [Q9NS15-2] ENST00000528516.5 A0A8I5KYV1 E9PKW1 E9PRF2 H0YC99 ENST00000689505.1 ENST00000301873.11 [Q9NS15-1] Q9NS15 ENST00000526927.6 H0YE75 B9EG76 E9PPT7 ENST00000532661.6 |