CHST11 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	18 studies	45% ± 23%	Explore
oligodendrocyte precursor cell	16 studies	73% ± 19%	Explore
endothelial cell	16 studies	30% ± 13%	Explore
astrocyte	15 studies	43% ± 17%	Explore
microglial cell	15 studies	70% ± 20%	Explore
natural killer cell	13 studies	34% ± 22%	Explore
mast cell	13 studies	51% ± 21%	Explore
myeloid cell	11 studies	44% ± 25%	Explore
GABAergic neuron	10 studies	49% ± 16%	Explore
T cell	9 studies	42% ± 20%	Explore
regulatory T cell	9 studies	35% ± 23%	Explore
glutamatergic neuron	8 studies	32% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	28% ± 18%	Explore
CD8-positive, alpha-beta T cell	8 studies	38% ± 22%	Explore
fibroblast	8 studies	28% ± 12%	Explore
B cell	8 studies	42% ± 15%	Explore
CD4-positive, alpha-beta T cell	7 studies	40% ± 23%	Explore
monocyte	7 studies	55% ± 22%	Explore
dendritic cell	7 studies	54% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	34% ± 23%	Explore
mature NK T cell	6 studies	29% ± 23%	Explore
gamma-delta T cell	6 studies	22% ± 7%	Explore
plasma cell	5 studies	41% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	39% ± 20%	Explore
pericyte	5 studies	29% ± 12%	Explore
type II pneumocyte	5 studies	30% ± 10%	Explore
interneuron	5 studies	53% ± 23%	Explore
plasmacytoid dendritic cell	5 studies	20% ± 4%	Explore
classical monocyte	4 studies	26% ± 6%	Explore
non-classical monocyte	4 studies	26% ± 9%	Explore
neuron	4 studies	29% ± 10%	Explore
retinal pigment epithelial cell	4 studies	51% ± 16%	Explore
mucosal invariant T cell	4 studies	35% ± 22%	Explore
lymphocyte	4 studies	60% ± 23%	Explore
innate lymphoid cell	4 studies	30% ± 23%	Explore
ciliated cell	4 studies	28% ± 12%	Explore
type I pneumocyte	4 studies	24% ± 3%	Explore
leukocyte	4 studies	76% ± 11%	Explore
conventional dendritic cell	3 studies	27% ± 6%	Explore
hematopoietic precursor cell	3 studies	52% ± 33%	Explore
GABAergic interneuron	3 studies	34% ± 7%	Explore
cardiac muscle cell	3 studies	17% ± 1%	Explore
mononuclear phagocyte	3 studies	39% ± 16%	Explore
retina horizontal cell	3 studies	20% ± 4%	Explore
endothelial cell of vascular tree	3 studies	16% ± 1%	Explore
connective tissue cell	3 studies	20% ± 4%	Explore
ependymal cell	3 studies	35% ± 12%	Explore
epithelial cell	3 studies	51% ± 23%	Explore
hematopoietic stem cell	3 studies	35% ± 21%	Explore
alveolar macrophage	3 studies	70% ± 12%	Explore
endothelial cell of lymphatic vessel	3 studies	20% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	26% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	22% ± 6%	Explore
mural cell	3 studies	29% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	33% ± 11%	Explore
lung	6 studies	31% ± 12%	Explore
peripheral blood	3 studies	24% ± 4%	Explore
heart	3 studies	21% ± 4%	Explore
adipose	3 studies	25% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1853.20	2632 / 2642	100%	56.93	705 / 705
lung	100%	3074.68	578 / 578	90%	21.01	1034 / 1155
breast	99%	956.36	454 / 459	91%	18.32	1013 / 1118
adrenal gland	100%	2749.67	258 / 258	88%	21.72	202 / 230
thymus	97%	836.68	634 / 653	90%	16.02	547 / 605
uterus	100%	2372.69	170 / 170	82%	18.91	377 / 459
skin	72%	560.31	1305 / 1809	99%	82.86	469 / 472
ovary	99%	1623.07	178 / 180	70%	10.66	300 / 430
kidney	84%	687.11	75 / 89	81%	17.52	730 / 901
stomach	100%	1278.19	359 / 359	64%	11.62	183 / 286
bladder	100%	1110.62	21 / 21	62%	15.26	310 / 504
pancreas	66%	570.89	216 / 328	94%	27.29	167 / 178
esophagus	83%	546.01	1198 / 1445	73%	19.31	134 / 183
intestine	99%	1169.35	958 / 966	48%	8.29	255 / 527
prostate	97%	1145.60	238 / 245	35%	3.39	174 / 502
eye	0%	0	0 / 0	100%	56.17	80 / 80
peripheral blood	100%	4853.76	929 / 929	0%	0	0 / 0
spleen	100%	2726.65	241 / 241	0%	0	0 / 0
adipose	100%	1246.53	1198 / 1204	0%	0	0 / 0
blood vessel	98%	1598.30	1314 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	33.06	28 / 29
tonsil	0%	0	0 / 0	89%	20.50	40 / 45
heart	74%	569.43	640 / 861	0%	0	0 / 0
liver	25%	114.36	57 / 226	30%	4.82	122 / 406
muscle	3%	14.12	28 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0030166	Biological process	proteoglycan biosynthetic process
GO_0030206	Biological process	chondroitin sulfate biosynthetic process
GO_0009791	Biological process	post-embryonic development
GO_0030512	Biological process	negative regulation of transforming growth factor beta receptor signaling pathway
GO_0001701	Biological process	in utero embryonic development
GO_0042733	Biological process	embryonic digit morphogenesis
GO_0016051	Biological process	carbohydrate biosynthetic process
GO_0002063	Biological process	chondrocyte development
GO_0033037	Biological process	polysaccharide localization
GO_0048703	Biological process	embryonic viscerocranium morphogenesis
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0036342	Biological process	post-anal tail morphogenesis
GO_0006915	Biological process	apoptotic process
GO_0048589	Biological process	developmental growth
GO_0007179	Biological process	transforming growth factor beta receptor signaling pathway
GO_0042127	Biological process	regulation of cell population proliferation
GO_0007585	Biological process	respiratory gaseous exchange by respiratory system
GO_0016020	Cellular component	membrane
GO_0000139	Cellular component	Golgi membrane
GO_0047756	Molecular function	chondroitin 4-sulfotransferase activity
GO_0001537	Molecular function	N-acetylgalactosamine 4-O-sulfotransferase activity
GO_0008146	Molecular function	sulfotransferase activity
GO_0050659	Molecular function	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

IV. Literature review

[source]

Gene name	CHST11
Protein name	Carbohydrate sulfotransferase (EC 2.8.2.-) Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Carbohydrate sulfotransferase 11
Synonyms
Description	FUNCTION: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
Accessions	ENST00000303694.6 [Q9NPF2-1] F8VXK3 ENST00000546689.1 F8VRG6 F8VXK7 ENST00000549260.5 [Q9NPF2-2] ENST00000547956.1 Q9NPF2 ENST00000549016.1

CHST11 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review