Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 25 studies | 49% ± 23% | |
| endothelial cell of lymphatic vessel | 20 studies | 66% ± 25% | |
| capillary endothelial cell | 12 studies | 39% ± 14% | |
| vein endothelial cell | 11 studies | 52% ± 18% | |
| endothelial cell of artery | 10 studies | 49% ± 21% | |
| endothelial cell of vascular tree | 9 studies | 56% ± 12% | |
| glomerular endothelial cell | 3 studies | 43% ± 11% |
Insufficient scRNA-seq data for expression of ECSCR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 2118.17 | 653 / 653 | 95% | 3.73 | 572 / 605 |
| breast | 100% | 2917.47 | 459 / 459 | 90% | 3.04 | 1004 / 1118 |
| esophagus | 96% | 1159.14 | 1386 / 1445 | 87% | 2.45 | 160 / 183 |
| prostate | 99% | 1005.04 | 242 / 245 | 78% | 2.02 | 391 / 502 |
| lung | 100% | 2996.40 | 578 / 578 | 75% | 1.85 | 871 / 1155 |
| kidney | 100% | 1085.70 | 89 / 89 | 74% | 6.01 | 664 / 901 |
| adrenal gland | 90% | 543.01 | 233 / 258 | 82% | 4.05 | 188 / 230 |
| bladder | 95% | 1725.67 | 20 / 21 | 75% | 2.27 | 379 / 504 |
| intestine | 95% | 938.22 | 922 / 966 | 73% | 2.01 | 385 / 527 |
| uterus | 100% | 1715.01 | 170 / 170 | 62% | 1.99 | 284 / 459 |
| stomach | 74% | 566.94 | 265 / 359 | 85% | 2.51 | 242 / 286 |
| skin | 67% | 544.14 | 1221 / 1809 | 44% | 1.10 | 208 / 472 |
| pancreas | 19% | 77.48 | 62 / 328 | 92% | 3.67 | 164 / 178 |
| ovary | 58% | 429.86 | 105 / 180 | 52% | 0.98 | 225 / 430 |
| adipose | 100% | 2944.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1109.24 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.95 | 1 / 1 |
| heart | 100% | 1280.77 | 858 / 861 | 0% | 0 | 0 / 0 |
| liver | 15% | 71.14 | 34 / 226 | 76% | 2.04 | 307 / 406 |
| blood vessel | 88% | 1042.68 | 1179 / 1335 | 0% | 0 | 0 / 0 |
| brain | 30% | 169.85 | 803 / 2642 | 56% | 2.12 | 397 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 2.86 | 25 / 29 |
| muscle | 74% | 379.04 | 594 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 1.05 | 26 / 45 |
| eye | 0% | 0 | 0 / 0 | 10% | 0.14 | 8 / 80 |
| peripheral blood | 1% | 3.39 | 5 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006915 | Biological process | apoptotic process |
| GO_0001525 | Biological process | angiogenesis |
| GO_1901800 | Biological process | positive regulation of proteasomal protein catabolic process |
| GO_0006935 | Biological process | chemotaxis |
| GO_0030154 | Biological process | cell differentiation |
| GO_2000353 | Biological process | positive regulation of endothelial cell apoptotic process |
| GO_0016525 | Biological process | negative regulation of angiogenesis |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ECSCR |
| Protein name | Endothelial cell-specific chemotaxis regulator (Apoptosis regulator through modulating IAP expression) (ARIA) (Endothelial cell-specific molecule 2) |
| Synonyms | ECSM2 |
| Description | FUNCTION: Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. . |
| Accessions | ENST00000673382.1 Q19T08 ENST00000618155.3 |
