Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 28 studies | 29% ± 11% | |
endothelial cell of lymphatic vessel | 22 studies | 49% ± 18% | |
astrocyte | 13 studies | 36% ± 18% | |
vein endothelial cell | 8 studies | 29% ± 17% | |
endothelial cell of vascular tree | 7 studies | 27% ± 11% | |
smooth muscle cell | 6 studies | 24% ± 12% | |
pericyte | 6 studies | 27% ± 13% | |
fibroblast | 6 studies | 26% ± 6% | |
capillary endothelial cell | 6 studies | 20% ± 7% | |
myofibroblast cell | 3 studies | 20% ± 4% |
Insufficient scRNA-seq data for expression of RHOJ at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 2643.64 | 459 / 459 | 95% | 12.14 | 1058 / 1118 |
brain | 92% | 1018.47 | 2442 / 2642 | 99% | 21.83 | 700 / 705 |
prostate | 100% | 2008.72 | 244 / 245 | 89% | 7.60 | 449 / 502 |
lung | 100% | 3383.77 | 578 / 578 | 87% | 8.13 | 1001 / 1155 |
thymus | 100% | 2367.94 | 651 / 653 | 86% | 8.67 | 523 / 605 |
esophagus | 95% | 1895.39 | 1379 / 1445 | 83% | 7.70 | 152 / 183 |
intestine | 98% | 1843.83 | 945 / 966 | 73% | 6.16 | 383 / 527 |
skin | 70% | 666.49 | 1265 / 1809 | 100% | 43.76 | 471 / 472 |
bladder | 100% | 2121.81 | 21 / 21 | 68% | 5.52 | 343 / 504 |
kidney | 91% | 1005.45 | 81 / 89 | 76% | 16.97 | 688 / 901 |
stomach | 77% | 1238.33 | 277 / 359 | 81% | 8.80 | 232 / 286 |
uterus | 99% | 2594.84 | 169 / 170 | 54% | 6.26 | 250 / 459 |
ovary | 99% | 1586.10 | 179 / 180 | 50% | 3.08 | 213 / 430 |
adrenal gland | 67% | 419.85 | 173 / 258 | 80% | 7.38 | 183 / 230 |
pancreas | 35% | 195.55 | 116 / 328 | 97% | 14.36 | 172 / 178 |
adipose | 100% | 2833.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1477.28 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 100% | 1512.52 | 859 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 28.23 | 79 / 80 |
blood vessel | 93% | 1413.03 | 1248 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 72% | 3.78 | 21 / 29 |
liver | 15% | 84.99 | 34 / 226 | 55% | 3.65 | 222 / 406 |
muscle | 69% | 423.52 | 554 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 58% | 3.42 | 26 / 45 |
peripheral blood | 0% | 0.65 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0090050 | Biological process | positive regulation of cell migration involved in sprouting angiogenesis |
GO_0007015 | Biological process | actin filament organization |
GO_0032488 | Biological process | Cdc42 protein signal transduction |
GO_0007163 | Biological process | establishment or maintenance of cell polarity |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0001525 | Biological process | angiogenesis |
GO_0008360 | Biological process | regulation of cell shape |
GO_0010594 | Biological process | regulation of endothelial cell migration |
GO_1903670 | Biological process | regulation of sprouting angiogenesis |
GO_0006897 | Biological process | endocytosis |
GO_0061299 | Biological process | retina vasculature morphogenesis in camera-type eye |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005886 | Cellular component | plasma membrane |
GO_0005525 | Molecular function | GTP binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RHOJ |
Protein name | Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein) Ras homolog family member J |
Synonyms | TCL RHOI RASL7B ARHJ |
Description | FUNCTION: Plasma membrane-associated small GTPase specifically involved in angiogenesis . Required for endothelial cell migration during vascular development via its interaction with GLUL . Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration . . |
Accessions | Q9H4E5 G3V4H1 ENST00000316754.8 [Q9H4E5-1] ENST00000555125.1 ENST00000557447.5 G3V476 |