MMRN1 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell of lymphatic vessel	29 studies	79% ± 13%	Explore
endothelial cell	15 studies	28% ± 13%	Explore
vein endothelial cell	10 studies	35% ± 13%	Explore
platelet	6 studies	28% ± 15%	Explore
hematopoietic stem cell	4 studies	29% ± 8%	Explore
endothelial cell of sinusoid	3 studies	29% ± 18%	Explore
megakaryocyte	3 studies	58% ± 14%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of MMRN1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	98%	3070.21	566 / 578	78%	4.44	896 / 1155
thymus	99%	6442.94	648 / 653	66%	3.07	400 / 605
esophagus	92%	1752.16	1336 / 1445	58%	3.41	107 / 183
breast	88%	3962.07	402 / 459	63%	4.11	699 / 1118
uterus	98%	2906.48	167 / 170	52%	2.46	238 / 459
prostate	64%	952.08	157 / 245	79%	3.73	399 / 502
intestine	92%	2501.53	893 / 966	50%	2.66	262 / 527
bladder	95%	1702.76	20 / 21	42%	1.61	211 / 504
stomach	60%	1079.56	216 / 359	57%	2.64	162 / 286
skin	64%	1304.23	1156 / 1809	38%	2.18	177 / 472
ureter	0%	0	0 / 0	100%	1.54	1 / 1
pancreas	12%	90.43	40 / 328	87%	9.48	154 / 178
adipose	96%	4167.14	1150 / 1204	0%	0	0 / 0
adrenal gland	31%	246.71	79 / 258	59%	3.20	136 / 230
ovary	54%	1163.06	98 / 180	27%	0.91	117 / 430
liver	27%	259.31	61 / 226	46%	1.38	188 / 406
kidney	9%	97.84	8 / 89	64%	7.18	576 / 901
blood vessel	72%	1790.16	966 / 1335	0%	0	0 / 0
brain	3%	24.79	79 / 2642	69%	3.00	488 / 705
lymph node	0%	0	0 / 0	69%	4.02	20 / 29
tonsil	0%	0	0 / 0	51%	1.78	23 / 45
eye	0%	0	0 / 0	35%	0.61	28 / 80
heart	31%	337.93	268 / 861	0%	0	0 / 0
muscle	9%	70.53	70 / 803	0%	0	0 / 0
peripheral blood	6%	44.16	56 / 929	0%	0	0 / 0
spleen	5%	40.14	11 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0033627	Biological process	cell adhesion mediated by integrin
GO_0007155	Biological process	cell adhesion
GO_0007596	Biological process	blood coagulation
GO_0061045	Biological process	negative regulation of wound healing
GO_1901731	Biological process	positive regulation of platelet aggregation
GO_1990972	Cellular component	multimerin complex
GO_0031091	Cellular component	platelet alpha granule
GO_0031093	Cellular component	platelet alpha granule lumen
GO_0005576	Cellular component	extracellular region
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005201	Molecular function	extracellular matrix structural constituent
GO_0030023	Molecular function	extracellular matrix constituent conferring elasticity
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

Gene name	MMRN1
Protein name	Multimerin 1 Multimerin-1 (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4) (Endothelial cell multimerin) [Cleaved into: Platelet glycoprotein Ia*; 155 kDa platelet multimerin (p-155) (p155)]
Synonyms	EMILIN4 ECM MMRN GPIA*
Description	FUNCTION: Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein. .
Accessions	ENST00000264790.7 [Q13201-1] ENST00000394980.5 [Q13201-1] Q13201 E7EPG1 ENST00000508372.1

MMRN1 report