ROBO4 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	37 studies	30% ± 11%	Explore
endothelial cell of lymphatic vessel	19 studies	28% ± 8%	Explore
capillary endothelial cell	15 studies	38% ± 12%	Explore
vein endothelial cell	11 studies	23% ± 6%	Explore
endothelial cell of vascular tree	7 studies	29% ± 12%	Explore
endothelial cell of artery	5 studies	25% ± 11%	Explore
glomerular endothelial cell	3 studies	61% ± 8%	Explore
pericyte	3 studies	22% ± 8%	Explore
endothelial cell of sinusoid	3 studies	37% ± 19%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ROBO4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	4124.57	653 / 653	95%	15.93	573 / 605
breast	100%	7237.76	459 / 459	94%	9.06	1053 / 1118
adrenal gland	95%	1514.12	245 / 258	89%	14.13	205 / 230
lung	100%	8481.33	578 / 578	81%	6.82	931 / 1155
kidney	100%	3150.36	89 / 89	78%	26.14	707 / 901
bladder	95%	2129.86	20 / 21	75%	5.27	379 / 504
prostate	93%	1798.07	227 / 245	77%	4.92	386 / 502
esophagus	84%	1725.77	1210 / 1445	83%	7.52	151 / 183
intestine	88%	1465.80	854 / 966	77%	5.55	408 / 527
stomach	81%	1044.55	289 / 359	83%	7.02	238 / 286
uterus	99%	3208.75	169 / 170	54%	3.86	247 / 459
brain	51%	588.45	1351 / 2642	100%	15.76	703 / 705
skin	66%	1005.82	1193 / 1809	71%	6.03	334 / 472
pancreas	23%	214.18	77 / 328	92%	7.73	163 / 178
liver	29%	320.70	66 / 226	80%	5.72	325 / 406
ovary	58%	803.04	105 / 180	44%	2.42	191 / 430
adipose	100%	8620.50	1204 / 1204	0%	0	0 / 0
spleen	100%	10971.41	241 / 241	0%	0	0 / 0
heart	98%	2454.46	843 / 861	0%	0	0 / 0
muscle	85%	1129.80	681 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	76%	4.33	34 / 45
lymph node	0%	0	0 / 0	69%	3.66	20 / 29
blood vessel	58%	1040.25	772 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	35%	1.91	28 / 80
peripheral blood	0%	1.91	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0061028	Biological process	establishment of endothelial barrier
GO_0001525	Biological process	angiogenesis
GO_0007156	Biological process	homophilic cell adhesion via plasma membrane adhesion molecules
GO_0030334	Biological process	regulation of cell migration
GO_0070593	Biological process	dendrite self-avoidance
GO_0007411	Biological process	axon guidance
GO_0030424	Cellular component	axon
GO_0070062	Cellular component	extracellular exosome
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0098632	Molecular function	cell-cell adhesion mediator activity
GO_0038023	Molecular function	signaling receptor activity
GO_0005515	Molecular function	protein binding

Gene name	ROBO4
Protein name	Roundabout guidance receptor 4 (cDNA FLJ54518, highly similar to Roundabout homolog 4) Roundabout homolog 4 (Magic roundabout)
Synonyms	UNQ421/PRO3674
Description	FUNCTION: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function . .
Accessions	ENST00000306534.8 [Q8WZ75-1] B4DYV8 ENST00000533054.5 Q8WZ75

ROBO4 report