RAB29 | OmnibusX

Name	Number of supported studies	Average coverage
natural killer cell	22 studies	27% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	34% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	24% ± 6%	Explore
CD8-positive, alpha-beta T cell	10 studies	24% ± 8%	Explore
mature NK T cell	10 studies	26% ± 6%	Explore
naive B cell	9 studies	17% ± 2%	Explore
B cell	8 studies	23% ± 4%	Explore
mucosal invariant T cell	8 studies	23% ± 3%	Explore
memory B cell	8 studies	19% ± 2%	Explore
gamma-delta T cell	8 studies	26% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	18% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	26% ± 5%	Explore
exhausted T cell	4 studies	26% ± 8%	Explore
epithelial cell of proximal tubule	4 studies	21% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	26% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	30% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 6%	Explore
regulatory T cell	4 studies	20% ± 3%	Explore
classical monocyte	3 studies	18% ± 2%	Explore
conventional dendritic cell	3 studies	33% ± 11%	Explore
non-classical monocyte	3 studies	24% ± 6%	Explore
myeloid cell	3 studies	19% ± 4%	Explore
dendritic cell	3 studies	35% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	18% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	7 studies	19% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	2814.08	653 / 653	100%	38.72	602 / 605
brain	99%	1206.37	2626 / 2642	100%	50.02	704 / 705
liver	100%	1342.42	226 / 226	99%	29.66	402 / 406
prostate	100%	1645.14	244 / 245	99%	34.08	499 / 502
lung	100%	1713.95	578 / 578	98%	25.65	1131 / 1155
bladder	100%	1972.29	21 / 21	97%	22.99	489 / 504
breast	100%	1595.22	459 / 459	97%	32.59	1083 / 1118
pancreas	97%	754.02	319 / 328	99%	29.85	176 / 178
skin	98%	1255.81	1764 / 1809	98%	40.64	461 / 472
stomach	100%	1216.72	359 / 359	95%	21.31	272 / 286
uterus	99%	993.04	169 / 170	95%	22.48	436 / 459
esophagus	99%	1871.18	1431 / 1445	95%	19.26	174 / 183
kidney	100%	4085.28	89 / 89	94%	43.84	843 / 901
ovary	100%	910.93	180 / 180	93%	16.85	402 / 430
intestine	100%	1692.79	964 / 966	93%	19.21	488 / 527
adrenal gland	100%	2166.29	258 / 258	78%	14.90	179 / 230
adipose	100%	1749.61	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	103.20	29 / 29
spleen	100%	2897.76	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	10.20	1 / 1
blood vessel	100%	1991.93	1334 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	21.82	44 / 45
peripheral blood	98%	1730.59	907 / 929	0%	0	0 / 0
heart	93%	988.44	802 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	89%	18.24	71 / 80
muscle	79%	492.30	635 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0050862	Biological process	positive regulation of T cell receptor signaling pathway
GO_0001921	Biological process	positive regulation of receptor recycling
GO_0009617	Biological process	response to bacterium
GO_0006886	Biological process	intracellular protein transport
GO_1990748	Biological process	cellular detoxification
GO_0032438	Biological process	melanosome organization
GO_1905279	Biological process	regulation of retrograde transport, endosome to Golgi
GO_0042147	Biological process	retrograde transport, endosome to Golgi
GO_0007030	Biological process	Golgi organization
GO_0044788	Biological process	modulation by host of viral process
GO_0007005	Biological process	mitochondrion organization
GO_0010977	Biological process	negative regulation of neuron projection development
GO_0030154	Biological process	cell differentiation
GO_0007416	Biological process	synapse assembly
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0090316	Biological process	positive regulation of intracellular protein transport
GO_0042110	Biological process	T cell activation
GO_0072657	Biological process	protein localization to membrane
GO_1903441	Biological process	protein localization to ciliary membrane
GO_0005801	Cellular component	cis-Golgi network
GO_0005856	Cellular component	cytoskeleton
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0012505	Cellular component	endomembrane system
GO_0055037	Cellular component	recycling endosome
GO_0005739	Cellular component	mitochondrion
GO_0005769	Cellular component	early endosome
GO_0005773	Cellular component	vacuole
GO_0070062	Cellular component	extracellular exosome
GO_0005794	Cellular component	Golgi apparatus
GO_0097708	Cellular component	intracellular vesicle
GO_0005802	Cellular component	trans-Golgi network
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0042470	Cellular component	melanosome
GO_0019003	Molecular function	GDP binding
GO_0031267	Molecular function	small GTPase binding
GO_0005525	Molecular function	GTP binding
GO_0070840	Molecular function	dynein complex binding
GO_0005515	Molecular function	protein binding
GO_0019894	Molecular function	kinesin binding
GO_0003924	Molecular function	GTPase activity

IV. Literature review

[source]

Gene name	RAB29
Protein name	RAB29, member RAS oncogene family Ras-related protein Rab-7L1 (Rab-7-like protein 1) (Ras-related protein Rab-29) Ras-related protein Rab
Synonyms	RAB7L1 hCG_19156
Description	FUNCTION: The small GTPases Rab are key regulators in vesicle trafficking . Essential for maintaining the integrity of the endosome-trans-Golgi network structure (By similarity). Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner . Recruits LRRK2 to the Golgi complex and stimulates LRRK2 kinase activity . Regulates neuronal process morphology in the intact central nervous system (CNS) (By similarity). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection . . FUNCTION: The small GTPases Rab are key regulators in vesicle trafficking. .
Accessions	ENST00000367139.8 [O14966-1] O14966 ENST00000414729.1 [O14966-1] Q6FGU7 ENST00000437324.6 [O14966-3] ENST00000235932.8 [O14966-1] E9PL56 ENST00000528078.1 ENST00000446390.6 [O14966-2]

RAB29 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review