Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 17 studies | 28% ± 12% | |
macrophage | 12 studies | 42% ± 17% | |
astrocyte | 11 studies | 37% ± 17% | |
microglial cell | 11 studies | 37% ± 13% | |
oligodendrocyte | 11 studies | 37% ± 12% | |
glutamatergic neuron | 10 studies | 48% ± 25% | |
oligodendrocyte precursor cell | 10 studies | 34% ± 14% | |
GABAergic neuron | 9 studies | 44% ± 24% | |
fibroblast | 8 studies | 24% ± 7% | |
myeloid cell | 7 studies | 32% ± 13% | |
epithelial cell | 7 studies | 30% ± 17% | |
dendritic cell | 7 studies | 24% ± 5% | |
neuron | 6 studies | 38% ± 16% | |
interneuron | 6 studies | 49% ± 24% | |
adipocyte | 6 studies | 22% ± 5% | |
mast cell | 6 studies | 23% ± 8% | |
cardiac muscle cell | 5 studies | 41% ± 11% | |
endothelial cell of lymphatic vessel | 5 studies | 27% ± 7% | |
monocyte | 5 studies | 37% ± 8% | |
smooth muscle cell | 5 studies | 21% ± 3% | |
type I pneumocyte | 5 studies | 26% ± 7% | |
type II pneumocyte | 5 studies | 24% ± 7% | |
granule cell | 4 studies | 27% ± 7% | |
amacrine cell | 4 studies | 23% ± 9% | |
pericyte | 4 studies | 22% ± 5% | |
GABAergic interneuron | 3 studies | 35% ± 4% | |
mononuclear phagocyte | 3 studies | 24% ± 7% | |
GABAergic amacrine cell | 3 studies | 26% ± 9% | |
glycinergic amacrine cell | 3 studies | 22% ± 5% | |
retinal rod cell | 3 studies | 16% ± 1% | |
ependymal cell | 3 studies | 29% ± 17% | |
T cell | 3 studies | 23% ± 5% | |
alveolar macrophage | 3 studies | 55% ± 11% | |
club cell | 3 studies | 23% ± 5% | |
natural killer cell | 3 studies | 22% ± 3% | |
lymphocyte | 3 studies | 30% ± 7% | |
basal cell | 3 studies | 36% ± 25% | |
goblet cell | 3 studies | 31% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2397.82 | 1445 / 1445 | 100% | 16.10 | 183 / 183 |
brain | 100% | 3278.68 | 2640 / 2642 | 100% | 17.54 | 705 / 705 |
breast | 100% | 2288.21 | 459 / 459 | 100% | 16.59 | 1117 / 1118 |
prostate | 100% | 2905.72 | 245 / 245 | 100% | 11.43 | 501 / 502 |
uterus | 100% | 2975.06 | 170 / 170 | 100% | 13.96 | 458 / 459 |
thymus | 100% | 4210.31 | 653 / 653 | 100% | 10.69 | 603 / 605 |
bladder | 100% | 2714.33 | 21 / 21 | 100% | 11.34 | 502 / 504 |
lung | 100% | 2913.88 | 578 / 578 | 100% | 14.60 | 1150 / 1155 |
ovary | 100% | 3199.87 | 180 / 180 | 99% | 10.70 | 427 / 430 |
skin | 100% | 2646.90 | 1808 / 1809 | 99% | 14.79 | 468 / 472 |
intestine | 100% | 2724.22 | 966 / 966 | 99% | 9.96 | 522 / 527 |
kidney | 100% | 2305.11 | 89 / 89 | 99% | 11.06 | 892 / 901 |
pancreas | 99% | 1368.73 | 326 / 328 | 99% | 11.13 | 176 / 178 |
stomach | 100% | 2156.87 | 359 / 359 | 98% | 10.61 | 281 / 286 |
adrenal gland | 100% | 2399.10 | 258 / 258 | 97% | 7.99 | 224 / 230 |
liver | 99% | 1136.01 | 224 / 226 | 77% | 4.44 | 314 / 406 |
adipose | 100% | 2165.77 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.57 | 29 / 29 |
muscle | 100% | 2922.95 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3642.99 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.47 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.18 | 1 / 1 |
blood vessel | 100% | 2196.16 | 1331 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 3625.09 | 922 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 2469.51 | 846 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 80% | 5.53 | 64 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006623 | Biological process | protein targeting to vacuole |
GO_0035542 | Biological process | regulation of SNARE complex assembly |
GO_0034058 | Biological process | endosomal vesicle fusion |
GO_0033263 | Cellular component | CORVET complex |
GO_0030897 | Cellular component | HOPS complex |
GO_0005770 | Cellular component | late endosome |
GO_0005769 | Cellular component | early endosome |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | VPS8 |
Protein name | VPS8 subunit of CORVET complex Vacuolar protein sorting-associated protein 8 homolog |
Synonyms | KIAA0804 |
Description | FUNCTION: Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations . Functions predominantly in APPL1-containing endosomes . . |
Accessions | ENST00000422105.5 ENST00000625842.3 [Q8N3P4-1] C9JKL0 H7C058 C9JPI1 ENST00000436792.6 [Q8N3P4-3] C9JG07 ENST00000421069.5 H7C322 C9JJN9 ENST00000426319.1 ENST00000424463.4 C9JP71 H7C1G7 ENST00000458721.5 C9JIA0 ENST00000453056.5 ENST00000446204.6 [Q8N3P4-2] Q8N3P4 ENST00000628962.1 F8WB24 ENST00000424721.5 ENST00000287546.8 ENST00000441141.5 ENST00000452140.5 H7C490 ENST00000445089.5 |