AP1S1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006898Biological processreceptor-mediated endocytosis
GO_0009615Biological processresponse to virus
GO_0006886Biological processintracellular protein transport
GO_0016192Biological processvesicle-mediated transport
GO_0060155Biological processplatelet dense granule organization
GO_0110010Biological processbasolateral protein secretion
GO_1903232Biological processmelanosome assembly
GO_0016020Cellular componentmembrane
GO_0005769Cellular componentearly endosome
GO_0030121Cellular componentAP-1 adaptor complex
GO_0005794Cellular componentGolgi apparatus
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005905Cellular componentclathrin-coated pit
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0005765Cellular componentlysosomal membrane
GO_0035615Molecular functionclathrin adaptor activity

IV. Literature review

[source]
Gene nameAP1S1
Protein nameAdaptor related protein complex 1 subunit sigma 1
AP complex subunit sigma
AP-1 complex subunit sigma-1A (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin)
SynonymsCLAPS1
AP19
DescriptionFUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. .

AccessionsENST00000646560.1
A0A2R8YGH5
ENST00000443943.5 [P61966-1]
H7C1E4
A0A2R8Y7S3
ENST00000646950.1
ENST00000429457.1
ENST00000337619.11 [P61966-1]
P61966