I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 8 studies | 48% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| enterocyte | 8 studies | 48% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 30% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 10562.14 | 226 / 226 | 50% | 232.53 | 202 / 406 |
| pancreas | 45% | 5.83 | 146 / 328 | 14% | 11.82 | 25 / 178 |
| intestine | 50% | 16006.70 | 481 / 966 | 5% | 1.54 | 28 / 527 |
| thymus | 49% | 5.75 | 322 / 653 | 1% | 0.08 | 5 / 605 |
| stomach | 36% | 11.52 | 128 / 359 | 12% | 8.52 | 33 / 286 |
| spleen | 41% | 13.31 | 98 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 32% | 27.39 | 457 / 1445 | 8% | 5.22 | 14 / 183 |
| uterus | 36% | 3.65 | 62 / 170 | 1% | 0.37 | 3 / 459 |
| heart | 36% | 4.24 | 306 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 34% | 4.47 | 88 / 258 | 0% | 0.01 | 1 / 230 |
| ovary | 33% | 10.39 | 60 / 180 | 0% | 0 | 0 / 430 |
| muscle | 32% | 4.13 | 260 / 803 | 0% | 0 | 0 / 0 |
| lung | 29% | 3.43 | 167 / 578 | 3% | 1.83 | 38 / 1155 |
| blood vessel | 29% | 5.00 | 389 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 28% | 3.10 | 68 / 245 | 0% | 0.01 | 2 / 502 |
| peripheral blood | 25% | 10.35 | 231 / 929 | 0% | 0 | 0 / 0 |
| breast | 24% | 20.49 | 110 / 459 | 0% | 0.01 | 1 / 1118 |
| kidney | 22% | 1.76 | 20 / 89 | 1% | 0.36 | 8 / 901 |
| adipose | 23% | 11.45 | 280 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 19% | 1.57 | 4 / 21 | 1% | 0.07 | 4 / 504 |
| skin | 19% | 5.76 | 348 / 1809 | 0% | 0.01 | 2 / 472 |
| brain | 16% | 1.64 | 423 / 2642 | 0% | 0.00 | 1 / 705 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.07 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034445 | Biological process | negative regulation of plasma lipoprotein oxidation |
| GO_0010898 | Biological process | positive regulation of triglyceride catabolic process |
| GO_0030300 | Biological process | regulation of intestinal cholesterol absorption |
| GO_0032374 | Biological process | regulation of cholesterol transport |
| GO_0034372 | Biological process | very-low-density lipoprotein particle remodeling |
| GO_0035634 | Biological process | response to stilbenoid |
| GO_0045723 | Biological process | positive regulation of fatty acid biosynthetic process |
| GO_0006982 | Biological process | response to lipid hydroperoxide |
| GO_0008203 | Biological process | cholesterol metabolic process |
| GO_0043691 | Biological process | reverse cholesterol transport |
| GO_0042744 | Biological process | hydrogen peroxide catabolic process |
| GO_0014012 | Biological process | peripheral nervous system axon regeneration |
| GO_0033700 | Biological process | phospholipid efflux |
| GO_0034375 | Biological process | high-density lipoprotein particle remodeling |
| GO_0042157 | Biological process | lipoprotein metabolic process |
| GO_0055090 | Biological process | acylglycerol homeostasis |
| GO_1905920 | Biological process | positive regulation of CoA-transferase activity |
| GO_0016042 | Biological process | lipid catabolic process |
| GO_0034371 | Biological process | chylomicron remodeling |
| GO_0046470 | Biological process | phosphatidylcholine metabolic process |
| GO_0034378 | Biological process | chylomicron assembly |
| GO_0051006 | Biological process | positive regulation of lipoprotein lipase activity |
| GO_0055088 | Biological process | lipid homeostasis |
| GO_0002227 | Biological process | innate immune response in mucosa |
| GO_0033344 | Biological process | cholesterol efflux |
| GO_0019430 | Biological process | removal of superoxide radicals |
| GO_0034014 | Biological process | response to triglyceride |
| GO_0006869 | Biological process | lipid transport |
| GO_0042632 | Biological process | cholesterol homeostasis |
| GO_0007159 | Biological process | leukocyte cell-cell adhesion |
| GO_0065005 | Biological process | protein-lipid complex assembly |
| GO_0042627 | Cellular component | chylomicron |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005769 | Cellular component | early endosome |
| GO_0034362 | Cellular component | low-density lipoprotein particle |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_1903561 | Cellular component | extracellular vesicle |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0034364 | Cellular component | high-density lipoprotein particle |
| GO_0072562 | Cellular component | blood microparticle |
| GO_0009986 | Cellular component | cell surface |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005829 | Cellular component | cytosol |
| GO_0045202 | Cellular component | synapse |
| GO_0034361 | Cellular component | very-low-density lipoprotein particle |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0008289 | Molecular function | lipid binding |
| GO_0005543 | Molecular function | phospholipid binding |
| GO_0060228 | Molecular function | phosphatidylcholine-sterol O-acyltransferase activator activity |
| GO_0120020 | Molecular function | cholesterol transfer activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0031210 | Molecular function | phosphatidylcholine binding |
| GO_0016209 | Molecular function | antioxidant activity |
| GO_0005319 | Molecular function | lipid transporter activity |
| GO_0005507 | Molecular function | copper ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | APOA4 |
| Protein name | Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4) Apolipoprotein A-IV (Apolipoprotein A4) |
| Synonyms | |
| Description | FUNCTION: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. FUNCTION: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. . |
| Accessions | Q13784 ENST00000357780.5 P06727 |
