Name | Number of supported studies | Average coverage | |
---|---|---|---|
microglial cell | 6 studies | 24% ± 9% | |
kidney loop of Henle epithelial cell | 5 studies | 48% ± 21% | |
retinal pigment epithelial cell | 4 studies | 20% ± 3% | |
macrophage | 4 studies | 27% ± 5% | |
epithelial cell | 3 studies | 26% ± 7% | |
astrocyte | 3 studies | 29% ± 12% | |
dendritic cell | 3 studies | 19% ± 3% | |
hepatocyte | 3 studies | 33% ± 13% | |
plasmacytoid dendritic cell | 3 studies | 28% ± 9% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 37% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
kidney | 4 studies | 27% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 4818.07 | 89 / 89 | 99% | 26.62 | 894 / 901 |
liver | 100% | 2515.08 | 226 / 226 | 97% | 8.18 | 395 / 406 |
esophagus | 100% | 756.82 | 1443 / 1445 | 97% | 7.73 | 178 / 183 |
skin | 100% | 1704.25 | 1809 / 1809 | 97% | 12.68 | 456 / 472 |
intestine | 100% | 868.83 | 965 / 966 | 96% | 7.12 | 507 / 527 |
adrenal gland | 100% | 1144.48 | 258 / 258 | 96% | 10.55 | 220 / 230 |
stomach | 100% | 1028.34 | 359 / 359 | 95% | 8.44 | 272 / 286 |
pancreas | 99% | 579.74 | 326 / 328 | 90% | 4.84 | 160 / 178 |
lung | 100% | 1377.88 | 577 / 578 | 89% | 5.12 | 1032 / 1155 |
uterus | 100% | 2012.05 | 170 / 170 | 85% | 6.16 | 390 / 459 |
brain | 91% | 657.64 | 2401 / 2642 | 90% | 3.76 | 634 / 705 |
bladder | 100% | 616.24 | 21 / 21 | 81% | 4.42 | 407 / 504 |
breast | 100% | 806.58 | 457 / 459 | 76% | 3.29 | 847 / 1118 |
prostate | 100% | 859.45 | 245 / 245 | 75% | 2.71 | 378 / 502 |
ovary | 100% | 3234.62 | 180 / 180 | 73% | 4.16 | 316 / 430 |
thymus | 100% | 1154.51 | 652 / 653 | 62% | 2.18 | 373 / 605 |
adipose | 100% | 969.91 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 897.81 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.69 | 1 / 1 |
muscle | 100% | 1069.87 | 800 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 98% | 618.92 | 1305 / 1335 | 0% | 0 | 0 / 0 |
heart | 89% | 379.12 | 766 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 81% | 4.58 | 65 / 80 |
tonsil | 0% | 0 | 0 / 0 | 76% | 2.80 | 34 / 45 |
lymph node | 0% | 0 | 0 / 0 | 62% | 2.33 | 18 / 29 |
peripheral blood | 52% | 237.55 | 482 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0003014 | Biological process | renal system process |
GO_0006897 | Biological process | endocytosis |
GO_0006821 | Biological process | chloride transport |
GO_0034220 | Biological process | monoatomic ion transmembrane transport |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005769 | Cellular component | early endosome |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005829 | Cellular component | cytosol |
GO_0008021 | Cellular component | synaptic vesicle |
GO_0010008 | Cellular component | endosome membrane |
GO_0045177 | Cellular component | apical part of cell |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0015297 | Molecular function | antiporter activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005247 | Molecular function | voltage-gated chloride channel activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CLCN5 |
Protein name | H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) Chloride channel protein Chloride voltage-gated channel 5 |
Synonyms | CLCK2 |
Description | FUNCTION: Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons . Important for normal acidification of the endosome lumen. May play an important role in renal tubular function. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable). . |
Accessions | ENST00000642885.1 [P51795-1] A0A2R8YF14 A0A2R8YGW0 P51795 A0A2R8Y6C4 ENST00000646398.1 ENST00000642383.1 ENST00000376088.7 [P51795-2] ENST00000307367.2 [P51795-1] ENST00000482218.2 ENST00000376091.8 [P51795-2] ENST00000643129.1 V9GYG7 ENST00000376108.7 [P51795-1] |