Insufficient scRNA-seq data for expression of SLC9A3 at single-cell level.
Insufficient scRNA-seq data for expression of SLC9A3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 88% | 2451.51 | 316 / 359 | 75% | 14.32 | 215 / 286 |
kidney | 100% | 2107.18 | 89 / 89 | 62% | 4.72 | 558 / 901 |
intestine | 78% | 1668.59 | 758 / 966 | 83% | 11.55 | 437 / 527 |
esophagus | 74% | 241.92 | 1076 / 1445 | 78% | 17.52 | 143 / 183 |
prostate | 92% | 184.95 | 225 / 245 | 30% | 1.03 | 149 / 502 |
uterus | 81% | 127.72 | 138 / 170 | 39% | 2.14 | 180 / 459 |
skin | 78% | 177.33 | 1419 / 1809 | 42% | 5.65 | 197 / 472 |
brain | 61% | 105.69 | 1618 / 2642 | 56% | 1.30 | 394 / 705 |
ovary | 92% | 177.64 | 166 / 180 | 20% | 0.58 | 88 / 430 |
thymus | 96% | 171.43 | 625 / 653 | 15% | 0.47 | 93 / 605 |
bladder | 71% | 76.86 | 15 / 21 | 36% | 3.48 | 181 / 504 |
pancreas | 42% | 41.98 | 137 / 328 | 65% | 5.24 | 116 / 178 |
adrenal gland | 72% | 74.34 | 187 / 258 | 23% | 0.55 | 52 / 230 |
lung | 57% | 56.71 | 331 / 578 | 36% | 2.36 | 420 / 1155 |
eye | 0% | 0 | 0 / 0 | 90% | 7.00 | 72 / 80 |
breast | 73% | 91.34 | 335 / 459 | 9% | 0.16 | 97 / 1118 |
spleen | 61% | 67.98 | 146 / 241 | 0% | 0 | 0 / 0 |
adipose | 54% | 61.74 | 655 / 1204 | 0% | 0 | 0 / 0 |
liver | 25% | 21.03 | 57 / 226 | 21% | 1.13 | 85 / 406 |
tonsil | 0% | 0 | 0 / 0 | 36% | 0.89 | 16 / 45 |
blood vessel | 32% | 35.88 | 427 / 1335 | 0% | 0 | 0 / 0 |
heart | 31% | 27.16 | 263 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 19% | 54.83 | 178 / 929 | 0% | 0 | 0 / 0 |
muscle | 5% | 4.01 | 43 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.05 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006811 | Biological process | monoatomic ion transport |
GO_0071805 | Biological process | potassium ion transmembrane transport |
GO_0098719 | Biological process | sodium ion import across plasma membrane |
GO_0051453 | Biological process | regulation of intracellular pH |
GO_1902600 | Biological process | proton transmembrane transport |
GO_0031526 | Cellular component | brush border membrane |
GO_0005903 | Cellular component | brush border |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005769 | Cellular component | early endosome |
GO_0031901 | Cellular component | early endosome membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0009986 | Cellular component | cell surface |
GO_0015385 | Molecular function | sodium:proton antiporter activity |
GO_0015386 | Molecular function | potassium:proton antiporter activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0035091 | Molecular function | phosphatidylinositol binding |
GO_0030165 | Molecular function | PDZ domain binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SLC9A3 |
Protein name | Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3) Sodium/hydrogen exchanger Sodium/hydrogen exchanger 3 |
Synonyms | NHE3 |
Description | FUNCTION: Plasma membrane Na(+)/H(+) antiporter . Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis (By similarity). Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation . . |
Accessions | P48764 ENST00000644203.1 A0A2R8Y780 ENST00000264938.8 [P48764-1] A0A0G2JQZ3 ENST00000626862.1 ENST00000628307.1 ENST00000514375.1 [P48764-2] |