SLC9A3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SLC9A3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC9A3 at tissue level.

III. Associated gene sets

GO_0006811Biological processmonoatomic ion transport
GO_0071805Biological processpotassium ion transmembrane transport
GO_0098719Biological processsodium ion import across plasma membrane
GO_0051453Biological processregulation of intracellular pH
GO_1902600Biological processproton transmembrane transport
GO_0031526Cellular componentbrush border membrane
GO_0005903Cellular componentbrush border
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0005769Cellular componentearly endosome
GO_0031901Cellular componentearly endosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0055038Cellular componentrecycling endosome membrane
GO_0009986Cellular componentcell surface
GO_0015385Molecular functionsodium:proton antiporter activity
GO_0015386Molecular functionpotassium:proton antiporter activity
GO_0042802Molecular functionidentical protein binding
GO_0035091Molecular functionphosphatidylinositol binding
GO_0030165Molecular functionPDZ domain binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC9A3
Protein nameSodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3)
Sodium/hydrogen exchanger
Sodium/hydrogen exchanger 3
SynonymsNHE3
DescriptionFUNCTION: Plasma membrane Na(+)/H(+) antiporter . Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis (By similarity). Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation . .

AccessionsP48764
ENST00000644203.1
A0A2R8Y780
ENST00000264938.8 [P48764-1]
A0A0G2JQZ3
ENST00000626862.1
ENST00000628307.1
ENST00000514375.1 [P48764-2]