Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 29 studies | 38% ± 14% | |
smooth muscle cell | 20 studies | 29% ± 11% | |
endothelial cell | 17 studies | 29% ± 12% | |
fibroblast | 17 studies | 27% ± 13% | |
endothelial cell of lymphatic vessel | 15 studies | 33% ± 13% | |
type I pneumocyte | 10 studies | 27% ± 11% | |
myofibroblast cell | 9 studies | 26% ± 14% | |
capillary endothelial cell | 9 studies | 24% ± 10% | |
endothelial cell of artery | 7 studies | 24% ± 4% | |
vein endothelial cell | 7 studies | 22% ± 8% | |
connective tissue cell | 6 studies | 31% ± 9% | |
basal cell | 5 studies | 20% ± 7% | |
endothelial cell of vascular tree | 5 studies | 21% ± 5% |
Insufficient scRNA-seq data for expression of EHD2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 20742.52 | 1441 / 1445 | 97% | 170.75 | 178 / 183 |
lung | 100% | 19495.04 | 578 / 578 | 94% | 127.04 | 1091 / 1155 |
thymus | 98% | 9744.65 | 643 / 653 | 96% | 114.00 | 578 / 605 |
breast | 100% | 24689.47 | 459 / 459 | 94% | 93.08 | 1049 / 1118 |
uterus | 100% | 19184.49 | 170 / 170 | 89% | 124.65 | 408 / 459 |
prostate | 98% | 11944.20 | 241 / 245 | 87% | 61.08 | 438 / 502 |
bladder | 100% | 20170.71 | 21 / 21 | 83% | 87.46 | 417 / 504 |
skin | 99% | 17334.96 | 1788 / 1809 | 83% | 74.55 | 393 / 472 |
ovary | 99% | 11978.50 | 179 / 180 | 82% | 64.93 | 353 / 430 |
adrenal gland | 97% | 10536.42 | 250 / 258 | 82% | 82.19 | 189 / 230 |
intestine | 94% | 15152.33 | 904 / 966 | 72% | 55.49 | 382 / 527 |
stomach | 70% | 8214.78 | 253 / 359 | 80% | 84.70 | 230 / 286 |
kidney | 47% | 3078.66 | 42 / 89 | 90% | 223.28 | 813 / 901 |
pancreas | 34% | 1494.03 | 111 / 328 | 94% | 129.01 | 167 / 178 |
adipose | 100% | 32354.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 27522.29 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 97% | 7200.93 | 233 / 241 | 0% | 0 | 0 / 0 |
heart | 96% | 7780.36 | 825 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 116.99 | 42 / 45 |
brain | 5% | 241.51 | 142 / 2642 | 74% | 52.19 | 520 / 705 |
eye | 0% | 0 | 0 / 0 | 74% | 38.82 | 59 / 80 |
liver | 9% | 488.48 | 21 / 226 | 46% | 25.50 | 187 / 406 |
muscle | 55% | 2703.20 | 438 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 12.54 | 10 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060271 | Biological process | cilium assembly |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0006897 | Biological process | endocytosis |
GO_0097320 | Biological process | plasma membrane tubulation |
GO_0032456 | Biological process | endocytic recycling |
GO_1901741 | Biological process | positive regulation of myoblast fusion |
GO_2001137 | Biological process | positive regulation of endocytic recycling |
GO_0030866 | Biological process | cortical actin cytoskeleton organization |
GO_0005886 | Cellular component | plasma membrane |
GO_0030139 | Cellular component | endocytic vesicle |
GO_0016020 | Cellular component | membrane |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005769 | Cellular component | early endosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0045171 | Cellular component | intercellular bridge |
GO_0005829 | Cellular component | cytosol |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0010008 | Cellular component | endosome membrane |
GO_0005901 | Cellular component | caveola |
GO_0005634 | Cellular component | nucleus |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0003676 | Molecular function | nucleic acid binding |
GO_0016787 | Molecular function | hydrolase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005525 | Molecular function | GTP binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | EHD2 |
Protein name | EH domain-containing protein 2 (PAST homolog 2) EH domain containing 2 |
Synonyms | PAST2 |
Description | FUNCTION: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes . Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane . . |
Accessions | ENST00000596225.5 ENST00000538399.1 [Q9NZN4-2] M0R1B9 ENST00000263277.8 [Q9NZN4-1] Q9NZN4 |