Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 11 studies | 29% ± 13% | |
endothelial cell | 10 studies | 27% ± 13% | |
microglial cell | 9 studies | 26% ± 9% | |
macrophage | 8 studies | 30% ± 7% | |
glutamatergic neuron | 7 studies | 42% ± 25% | |
GABAergic neuron | 7 studies | 38% ± 20% | |
oligodendrocyte | 7 studies | 25% ± 7% | |
interneuron | 6 studies | 35% ± 21% | |
oligodendrocyte precursor cell | 6 studies | 27% ± 10% | |
epithelial cell | 5 studies | 26% ± 10% | |
fibroblast | 5 studies | 21% ± 5% | |
neuron | 4 studies | 30% ± 12% | |
cardiac muscle cell | 4 studies | 19% ± 1% | |
myeloid cell | 4 studies | 22% ± 4% | |
type I pneumocyte | 4 studies | 20% ± 5% | |
GABAergic interneuron | 3 studies | 22% ± 9% | |
granule cell | 3 studies | 22% ± 0% | |
ciliated cell | 3 studies | 21% ± 3% | |
alveolar macrophage | 3 studies | 25% ± 7% | |
endothelial cell of lymphatic vessel | 3 studies | 18% ± 2% | |
monocyte | 3 studies | 22% ± 4% | |
lymphocyte | 3 studies | 22% ± 5% | |
goblet cell | 3 studies | 26% ± 11% | |
transit amplifying cell | 3 studies | 27% ± 17% | |
adipocyte | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 10 studies | 34% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4281.46 | 1445 / 1445 | 99% | 20.95 | 182 / 183 |
brain | 100% | 3516.20 | 2632 / 2642 | 100% | 38.93 | 702 / 705 |
lung | 100% | 4658.51 | 578 / 578 | 99% | 13.77 | 1143 / 1155 |
stomach | 100% | 3640.75 | 359 / 359 | 99% | 14.40 | 282 / 286 |
skin | 100% | 4825.29 | 1809 / 1809 | 98% | 21.41 | 462 / 472 |
intestine | 100% | 6787.67 | 966 / 966 | 98% | 11.80 | 515 / 527 |
ovary | 100% | 5580.15 | 180 / 180 | 97% | 12.89 | 419 / 430 |
breast | 100% | 4302.90 | 459 / 459 | 97% | 17.03 | 1089 / 1118 |
thymus | 100% | 4254.67 | 653 / 653 | 97% | 17.97 | 587 / 605 |
kidney | 100% | 2869.43 | 89 / 89 | 96% | 13.66 | 862 / 901 |
bladder | 100% | 4860.48 | 21 / 21 | 96% | 10.70 | 482 / 504 |
pancreas | 99% | 1870.63 | 326 / 328 | 96% | 9.93 | 171 / 178 |
prostate | 100% | 4129.27 | 245 / 245 | 94% | 12.82 | 474 / 502 |
uterus | 100% | 6282.95 | 170 / 170 | 94% | 11.41 | 431 / 459 |
adrenal gland | 100% | 5303.61 | 258 / 258 | 83% | 8.08 | 190 / 230 |
liver | 100% | 1953.99 | 226 / 226 | 70% | 4.89 | 283 / 406 |
adipose | 100% | 4088.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 4503.73 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4182.68 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 2800.12 | 798 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 20.20 | 79 / 80 |
heart | 98% | 2299.41 | 847 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 16.05 | 43 / 45 |
peripheral blood | 84% | 1923.36 | 784 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 76% | 7.92 | 22 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0048549 | Biological process | positive regulation of pinocytosis |
GO_0006897 | Biological process | endocytosis |
GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
GO_0016197 | Biological process | endosomal transport |
GO_0090160 | Biological process | Golgi to lysosome transport |
GO_0034058 | Biological process | endosomal vesicle fusion |
GO_0016020 | Cellular component | membrane |
GO_0005769 | Cellular component | early endosome |
GO_0044354 | Cellular component | macropinosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0030904 | Cellular component | retromer complex |
GO_0005829 | Cellular component | cytosol |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0010008 | Cellular component | endosome membrane |
GO_0005768 | Cellular component | endosome |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0031267 | Molecular function | small GTPase binding |
GO_0046872 | Molecular function | metal ion binding |
GO_1901981 | Molecular function | phosphatidylinositol phosphate binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ANKFY1 |
Protein name | Ankyrin repeat and FYVE domain containing 1 Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) |
Synonyms | KIAA1255 ANKHZN |
Description | FUNCTION: Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport. . |
Accessions | ENST00000570535.5 [Q9P2R3-4] ENST00000341657.9 [Q9P2R3-1] Q9P2R3 ENST00000574736.1 K7EPT2 ENST00000648043.1 [Q9P2R3-1] ENST00000575298.1 ENST00000574367.5 [Q9P2R3-2] I3L1Z9 I3L3P8 ENST00000572412.5 |