Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 7 studies | 29% ± 13% | |
endothelial cell | 6 studies | 19% ± 2% | |
oligodendrocyte | 6 studies | 27% ± 9% | |
macrophage | 5 studies | 18% ± 2% | |
abnormal cell | 4 studies | 20% ± 5% | |
astrocyte | 4 studies | 24% ± 4% | |
ciliated cell | 3 studies | 29% ± 7% | |
fibroblast | 3 studies | 18% ± 3% | |
GABAergic neuron | 3 studies | 33% ± 9% | |
glutamatergic neuron | 3 studies | 38% ± 12% | |
oligodendrocyte precursor cell | 3 studies | 25% ± 5% | |
dendritic cell | 3 studies | 20% ± 4% | |
basal cell | 3 studies | 33% ± 4% | |
transit amplifying cell | 3 studies | 25% ± 13% | |
goblet cell | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2351.52 | 1445 / 1445 | 100% | 24.23 | 183 / 183 |
intestine | 100% | 2135.32 | 966 / 966 | 100% | 20.58 | 527 / 527 |
ovary | 100% | 2103.96 | 180 / 180 | 100% | 21.59 | 430 / 430 |
prostate | 100% | 2578.05 | 245 / 245 | 100% | 26.05 | 502 / 502 |
stomach | 100% | 1688.45 | 359 / 359 | 100% | 20.17 | 286 / 286 |
brain | 100% | 2231.67 | 2641 / 2642 | 100% | 30.10 | 705 / 705 |
breast | 100% | 2237.57 | 459 / 459 | 100% | 24.88 | 1117 / 1118 |
lung | 100% | 1731.02 | 577 / 578 | 100% | 23.65 | 1155 / 1155 |
uterus | 100% | 2684.44 | 170 / 170 | 100% | 23.20 | 458 / 459 |
bladder | 100% | 2187.71 | 21 / 21 | 100% | 21.08 | 502 / 504 |
thymus | 100% | 2214.90 | 653 / 653 | 100% | 18.66 | 602 / 605 |
kidney | 100% | 1967.72 | 89 / 89 | 99% | 19.72 | 893 / 901 |
skin | 100% | 2626.21 | 1809 / 1809 | 99% | 21.53 | 466 / 472 |
pancreas | 100% | 1133.19 | 327 / 328 | 99% | 18.55 | 176 / 178 |
liver | 100% | 1023.55 | 226 / 226 | 97% | 11.60 | 395 / 406 |
adrenal gland | 100% | 1603.82 | 258 / 258 | 93% | 10.83 | 215 / 230 |
adipose | 100% | 1922.64 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2432.46 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 17.89 | 29 / 29 |
muscle | 100% | 2298.98 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1839.18 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 21.15 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.38 | 1 / 1 |
heart | 96% | 1325.50 | 830 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 12.55 | 76 / 80 |
peripheral blood | 95% | 1667.26 | 880 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000281 | Biological process | mitotic cytokinesis |
GO_0046580 | Biological process | negative regulation of Ras protein signal transduction |
GO_0051898 | Biological process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0070536 | Biological process | protein K63-linked deubiquitination |
GO_0110088 | Biological process | hippocampal neuron apoptotic process |
GO_0006508 | Biological process | proteolysis |
GO_0016579 | Biological process | protein deubiquitination |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0110091 | Biological process | negative regulation of hippocampal neuron apoptotic process |
GO_0007259 | Biological process | cell surface receptor signaling pathway via JAK-STAT |
GO_0005886 | Cellular component | plasma membrane |
GO_0005769 | Cellular component | early endosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0032154 | Cellular component | cleavage furrow |
GO_0005768 | Cellular component | endosome |
GO_0005634 | Cellular component | nucleus |
GO_0140492 | Molecular function | metal-dependent deubiquitinase activity |
GO_0101005 | Molecular function | deubiquitinase activity |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0061578 | Molecular function | K63-linked deubiquitinase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | STAMBP |
Protein name | STAM binding protein STAM-binding protein Alternative protein STAMBP STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase) |
Synonyms | AMSH |
Description | FUNCTION: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains . Does not cleave 'Lys-48'-linked polyubiquitin chains . Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF . Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7 . Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes . Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization . Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways . . |
Accessions | ENST00000684312.1 [O95630-1] A0A804HHU9 A0A804HKL2 ENST00000683718.1 ENST00000682558.1 [O95630-1] ENST00000683317.1 [O95630-1] ENST00000432295 ENST00000683594.1 ENST00000683149.1 ENST00000409707.6 [O95630-1] A0A804HL38 ENST00000683902.1 ENST00000682379.1 [O95630-1] A0A804HKA6 ENST00000682848.1 ENST00000682592.1 ENST00000684716.1 ENST00000683728.1 A0A804HIJ2 ENST00000682387.1 ENST00000684758.1 ENST00000682799.1 ENST00000683877.1 ENST00000536064.2 A0A804HJC8 ENST00000684697.1 A0A804HIF8 ENST00000682157.1 ENST00000683852.1 ENST00000682998.1 ENST00000394070.7 [O95630-1] ENST00000683818.1 [O95630-1] ENST00000683417.1 ENST00000683530.1 ENST00000683434.1 ENST00000682847.1 [O95630-1] ENST00000684200.1 ENST00000682351.1 [O95630-1] ENST00000682784.1 ENST00000684355.1 ENST00000339566.7 [O95630-1] ENST00000682105.1 A0A804HJ64 ENST00000684095.1 [O95630-1] O95630 ENST00000683349.1 A0A804HIV0 ENST00000394073.6 [O95630-1] A0A804HI64 ENST00000682352.1 A0A804HII8 A0A804HJE8 ENST00000684671.1 ENST00000683518.1 [O95630-1] ENST00000683582.1 A0A804HHV2 C9JK83 ENST00000684321.1 ENST00000684426.1 ENST00000684703.1 ENST00000683036.1 [O95630-1] C9JEK5 ENST00000682851.1 F5H5B9 ENST00000432295.7 [O95630-2] ENST00000684774.1 ENST00000683391.1 ENST00000478946.2 ENST00000683247.1 A0A804HJD9 ENST00000683016.1 ENST00000684585.1 [O95630-1] A0A804HL27 L8ECD1 ENST00000424659.6 ENST00000683304.1 A0A804HJS0 ENST00000682423.1 ENST00000684337.1 ENST00000683928.1 |