Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 11 studies | 23% ± 7% | |
| natural killer cell | 10 studies | 20% ± 4% | |
| ciliated cell | 8 studies | 23% ± 8% | |
| endothelial cell | 8 studies | 23% ± 9% | |
| B cell | 6 studies | 22% ± 4% | |
| classical monocyte | 6 studies | 25% ± 12% | |
| epithelial cell | 6 studies | 33% ± 11% | |
| endothelial cell of lymphatic vessel | 5 studies | 25% ± 11% | |
| gamma-delta T cell | 5 studies | 22% ± 5% | |
| non-classical monocyte | 4 studies | 36% ± 15% | |
| CD8-positive, alpha-beta T cell | 4 studies | 19% ± 3% | |
| myeloid cell | 4 studies | 32% ± 3% | |
| oligodendrocyte | 4 studies | 21% ± 3% | |
| goblet cell | 4 studies | 20% ± 5% | |
| CD16-negative, CD56-bright natural killer cell, human | 3 studies | 20% ± 3% | |
| conventional dendritic cell | 3 studies | 26% ± 8% | |
| mature NK T cell | 3 studies | 17% ± 2% | |
| memory B cell | 3 studies | 18% ± 1% | |
| microglial cell | 3 studies | 21% ± 5% | |
| T cell | 3 studies | 20% ± 2% | |
| fibroblast | 3 studies | 17% ± 1% | |
| intraepithelial lymphocyte | 3 studies | 17% ± 1% | |
| astrocyte | 3 studies | 29% ± 3% | |
| glutamatergic neuron | 3 studies | 37% ± 14% | |
| oligodendrocyte precursor cell | 3 studies | 23% ± 3% | |
| monocyte | 3 studies | 22% ± 3% | |
| leukocyte | 3 studies | 18% ± 1% | |
| alveolar macrophage | 3 studies | 27% ± 11% | |
| basal cell | 3 studies | 27% ± 5% | |
| transit amplifying cell | 3 studies | 23% ± 9% | |
| neuron | 3 studies | 28% ± 9% | |
| CD8-positive, alpha-beta memory T cell | 3 studies | 16% ± 1% | |
| abnormal cell | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4136.95 | 1445 / 1445 | 100% | 22.31 | 183 / 183 |
| pancreas | 100% | 2629.71 | 328 / 328 | 100% | 23.15 | 178 / 178 |
| prostate | 100% | 5740.11 | 245 / 245 | 100% | 29.08 | 502 / 502 |
| skin | 100% | 4132.04 | 1809 / 1809 | 100% | 40.93 | 472 / 472 |
| stomach | 100% | 3695.92 | 359 / 359 | 100% | 19.95 | 286 / 286 |
| thymus | 100% | 6581.03 | 653 / 653 | 100% | 32.24 | 605 / 605 |
| uterus | 100% | 5114.77 | 170 / 170 | 100% | 23.18 | 459 / 459 |
| lung | 100% | 4811.71 | 578 / 578 | 100% | 23.38 | 1154 / 1155 |
| brain | 100% | 3921.33 | 2637 / 2642 | 100% | 32.19 | 705 / 705 |
| intestine | 100% | 4814.29 | 966 / 966 | 100% | 21.86 | 526 / 527 |
| bladder | 100% | 4239.29 | 21 / 21 | 100% | 24.80 | 503 / 504 |
| kidney | 100% | 4691.89 | 89 / 89 | 100% | 20.31 | 898 / 901 |
| breast | 100% | 3937.09 | 459 / 459 | 100% | 23.29 | 1113 / 1118 |
| ovary | 100% | 5764.93 | 180 / 180 | 100% | 17.60 | 428 / 430 |
| liver | 100% | 2965.17 | 226 / 226 | 99% | 15.80 | 403 / 406 |
| adrenal gland | 100% | 6217.65 | 258 / 258 | 99% | 18.90 | 228 / 230 |
| adipose | 100% | 3405.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 32.12 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 47.43 | 29 / 29 |
| muscle | 100% | 3223.18 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 7528.43 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 20.94 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 22.81 | 1 / 1 |
| blood vessel | 100% | 3134.17 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 3856.61 | 919 / 929 | 0% | 0 | 0 / 0 |
| heart | 98% | 2289.57 | 843 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006886 | Biological process | intracellular protein transport |
| GO_0034394 | Biological process | protein localization to cell surface |
| GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
| GO_0045732 | Biological process | positive regulation of protein catabolic process |
| GO_0006893 | Biological process | Golgi to plasma membrane transport |
| GO_0030163 | Biological process | protein catabolic process |
| GO_0008104 | Biological process | protein localization |
| GO_0043001 | Biological process | Golgi to plasma membrane protein transport |
| GO_1903441 | Biological process | protein localization to ciliary membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005769 | Cellular component | early endosome |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005802 | Cellular component | trans-Golgi network |
| GO_0005829 | Cellular component | cytosol |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0010008 | Cellular component | endosome membrane |
| GO_0031267 | Molecular function | small GTPase binding |
| GO_0035091 | Molecular function | phosphatidylinositol binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0043130 | Molecular function | ubiquitin binding |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | GGA1 |
| Protein name | ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) Golgi associated, gamma adaptin ear containing, ARF binding protein 1 |
| Synonyms | |
| Description | FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif . Mediates export of the GPCR receptor ADRA2B to the cell surface . Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane (By similarity). Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endosomes to the trans-Golgi network . . |
| Accessions | Q9UJY5 ENST00000411501.5 ENST00000449944.5 B0QYS2 ENST00000405147.7 B0QYR9 ENST00000439161.5 ENST00000343632.9 [Q9UJY5-1] ENST00000431745.5 ENST00000413251.5 ENST00000326597.6 ENST00000381756.9 [Q9UJY5-6] ENST00000429218.5 B0QYS0 ENST00000423024.1 ENST00000325180.12 [Q9UJY5-4] ENST00000406772.5 [Q9UJY5-3] B0QYS5 B0QYS3 B0QYR5 ENST00000447515.5 B0QYS1 B0QYR8 ENST00000453208.5 B0QYR6 |