RIN3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0002091Biological processnegative regulation of receptor internalization
GO_0097494Biological processregulation of vesicle size
GO_0006897Biological processendocytosis
GO_0060755Biological processnegative regulation of mast cell chemotaxis
GO_0030424Cellular componentaxon
GO_0005829Cellular componentcytosol
GO_0030425Cellular componentdendrite
GO_0043025Cellular componentneuronal cell body
GO_0031982Cellular componentvesicle
GO_0031410Cellular componentcytoplasmic vesicle
GO_0005737Cellular componentcytoplasm
GO_0030139Cellular componentendocytic vesicle
GO_0005769Cellular componentearly endosome
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameRIN3
Protein nameRas and Rab interactor 3
RIN3 protein
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
SynonymshCG_2029104
DescriptionFUNCTION: Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function. .

AccessionsENST00000555589.5
G3V534
ENST00000620541.4
A0A087WWY9
ENST00000557762.1
ENST00000216487.12 [Q8TB24-1]
H0YJ83
ENST00000556418.1
G3V2I7
Q6NSK7
Q8TB24