ECPAS report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043248Biological processproteasome assembly
GO_0036503Biological processERAD pathway
GO_0000502Cellular componentproteasome complex
GO_0031410Cellular componentcytoplasmic vesicle
GO_0030139Cellular componentendocytic vesicle
GO_0016020Cellular componentmembrane
GO_0005769Cellular componentearly endosome
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005802Cellular componenttrans-Golgi network
GO_0005783Cellular componentendoplasmic reticulum
GO_0005770Cellular componentlate endosome
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0005771Cellular componentmultivesicular body
GO_0030134Cellular componentCOPII-coated ER to Golgi transport vesicle
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0070628Molecular functionproteasome binding
GO_0060090Molecular functionmolecular adaptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameECPAS
Protein nameEcm29 proteasome adaptor and scaffold
Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog)
SynonymsECM29
KIAA0368
DescriptionFUNCTION: Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolysis . Promotes proteasome dissociation under oxidative stress (By similarity). .

AccessionsJ3KN16
Q5VYK3
ENST00000602978.1
R4GMY3
ENST00000602447.5
F6XAQ5
R4GMY1
ENST00000259335.8
ENST00000374383.1
ENST00000684092.1 [Q5VYK3-2]