RCSD1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	44 studies	47% ± 17%	Explore
natural killer cell	32 studies	29% ± 9%	Explore
CD4-positive, alpha-beta T cell	27 studies	29% ± 9%	Explore
CD8-positive, alpha-beta T cell	26 studies	27% ± 8%	Explore
T cell	25 studies	30% ± 9%	Explore
regulatory T cell	25 studies	36% ± 12%	Explore
non-classical monocyte	23 studies	31% ± 15%	Explore
memory B cell	20 studies	47% ± 12%	Explore
naive B cell	20 studies	53% ± 12%	Explore
classical monocyte	17 studies	37% ± 15%	Explore
macrophage	17 studies	35% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	31% ± 10%	Explore
gamma-delta T cell	16 studies	31% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	30% ± 9%	Explore
mature NK T cell	14 studies	28% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	31% ± 10%	Explore
monocyte	14 studies	30% ± 9%	Explore
microglial cell	14 studies	40% ± 19%	Explore
conventional dendritic cell	13 studies	28% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	32% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	32% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	32% ± 11%	Explore
mucosal invariant T cell	11 studies	33% ± 10%	Explore
pericyte	11 studies	22% ± 4%	Explore
dendritic cell	10 studies	30% ± 9%	Explore
plasmacytoid dendritic cell	10 studies	29% ± 6%	Explore
myeloid cell	10 studies	31% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	31% ± 9%	Explore
endothelial cell of lymphatic vessel	9 studies	24% ± 5%	Explore
endothelial cell	9 studies	28% ± 10%	Explore
innate lymphoid cell	8 studies	35% ± 14%	Explore
smooth muscle cell	8 studies	21% ± 6%	Explore
mast cell	8 studies	26% ± 6%	Explore
precursor B cell	7 studies	77% ± 21%	Explore
immature B cell	7 studies	69% ± 15%	Explore
plasma cell	6 studies	32% ± 6%	Explore
leukocyte	6 studies	41% ± 15%	Explore
hematopoietic stem cell	6 studies	43% ± 13%	Explore
hematopoietic precursor cell	5 studies	43% ± 11%	Explore
plasmablast	5 studies	47% ± 25%	Explore
lymphocyte	5 studies	39% ± 11%	Explore
pro-B cell	5 studies	85% ± 10%	Explore
capillary endothelial cell	5 studies	22% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	30% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	39% ± 11%	Explore
T follicular helper cell	5 studies	28% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	28% ± 7%	Explore
exhausted T cell	4 studies	37% ± 10%	Explore
cardiac muscle cell	4 studies	22% ± 3%	Explore
mononuclear phagocyte	4 studies	29% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	42% ± 9%	Explore
T-helper 17 cell	4 studies	23% ± 4%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	24% ± 6%	Explore
double negative thymocyte	4 studies	39% ± 15%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	31% ± 9%	Explore
CD4-positive helper T cell	3 studies	19% ± 2%	Explore
fibroblast	3 studies	18% ± 1%	Explore
germinal center B cell	3 studies	42% ± 1%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	27% ± 14%	Explore
neutrophil	3 studies	18% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	43% ± 6%	Explore
T-helper 1 cell	3 studies	32% ± 7%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	24% ± 10%	Explore
mural cell	3 studies	30% ± 11%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	36% ± 16%	Explore
bone marrow	4 studies	31% ± 12%	Explore
lymph node	4 studies	40% ± 11%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	1280.29	458 / 459	96%	10.05	1077 / 1118
thymus	98%	1035.29	640 / 653	94%	17.14	568 / 605
lung	100%	1946.11	577 / 578	90%	8.01	1034 / 1155
stomach	96%	832.63	346 / 359	79%	5.89	227 / 286
kidney	85%	640.56	76 / 89	89%	12.70	802 / 901
bladder	100%	1316.62	21 / 21	69%	4.92	350 / 504
intestine	93%	1791.20	897 / 966	75%	4.74	397 / 527
brain	65%	404.88	1710 / 2642	100%	12.15	702 / 705
uterus	81%	447.30	137 / 170	73%	4.89	333 / 459
adrenal gland	81%	491.36	208 / 258	72%	4.43	166 / 230
prostate	79%	550.83	193 / 245	72%	3.44	362 / 502
esophagus	81%	745.42	1165 / 1445	67%	3.92	123 / 183
skin	38%	204.72	693 / 1809	78%	9.71	369 / 472
adipose	100%	1772.18	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	92.87	29 / 29
muscle	100%	3131.65	803 / 803	0%	0	0 / 0
peripheral blood	100%	6165.23	929 / 929	0%	0	0 / 0
spleen	100%	7352.73	241 / 241	0%	0	0 / 0
heart	98%	1786.79	847 / 861	0%	0	0 / 0
pancreas	6%	33.10	20 / 328	92%	10.25	164 / 178
blood vessel	94%	1188.04	1254 / 1335	0%	0	0 / 0
liver	35%	159.74	80 / 226	57%	3.03	231 / 406
ovary	33%	175.95	60 / 180	55%	2.23	236 / 430
tonsil	0%	0	0 / 0	82%	8.82	37 / 45
eye	0%	0	0 / 0	29%	1.33	23 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1