Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 11 studies | 30% ± 12% | |
| macrophage | 5 studies | 20% ± 1% | |
| epithelial cell | 4 studies | 23% ± 4% | |
| astrocyte | 4 studies | 26% ± 5% | |
| endothelial cell | 4 studies | 19% ± 6% | |
| GABAergic neuron | 3 studies | 41% ± 5% | |
| glutamatergic neuron | 3 studies | 49% ± 6% | |
| microglial cell | 3 studies | 22% ± 4% | |
| oligodendrocyte precursor cell | 3 studies | 26% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 45% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2263.88 | 1445 / 1445 | 100% | 59.86 | 183 / 183 |
| ovary | 100% | 1892.46 | 180 / 180 | 100% | 41.06 | 430 / 430 |
| stomach | 100% | 1914.06 | 359 / 359 | 100% | 50.29 | 286 / 286 |
| breast | 100% | 2610.17 | 459 / 459 | 100% | 77.07 | 1114 / 1118 |
| lung | 100% | 2133.07 | 576 / 578 | 100% | 41.00 | 1154 / 1155 |
| intestine | 100% | 2414.26 | 966 / 966 | 99% | 41.89 | 524 / 527 |
| brain | 99% | 1712.62 | 2628 / 2642 | 100% | 37.26 | 703 / 705 |
| thymus | 100% | 2452.03 | 653 / 653 | 98% | 31.23 | 595 / 605 |
| prostate | 100% | 1936.58 | 245 / 245 | 98% | 37.04 | 492 / 502 |
| skin | 100% | 3276.19 | 1809 / 1809 | 98% | 55.52 | 461 / 472 |
| bladder | 100% | 2393.62 | 21 / 21 | 98% | 36.23 | 492 / 504 |
| uterus | 100% | 2357.40 | 170 / 170 | 98% | 31.63 | 448 / 459 |
| pancreas | 98% | 1255.38 | 322 / 328 | 99% | 33.61 | 176 / 178 |
| kidney | 100% | 1956.39 | 89 / 89 | 95% | 30.94 | 859 / 901 |
| liver | 99% | 971.03 | 224 / 226 | 93% | 23.95 | 377 / 406 |
| adrenal gland | 100% | 3183.09 | 258 / 258 | 91% | 29.32 | 209 / 230 |
| adipose | 100% | 2722.96 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2515.08 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 30.43 | 29 / 29 |
| spleen | 100% | 2627.76 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 34.72 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.66 | 1 / 1 |
| muscle | 100% | 1777.18 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 95% | 1421.54 | 815 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 90% | 1446.37 | 838 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 50.95 | 71 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007040 | Biological process | lysosome organization |
| GO_0010976 | Biological process | positive regulation of neuron projection development |
| GO_0097494 | Biological process | regulation of vesicle size |
| GO_0051125 | Biological process | regulation of actin nucleation |
| GO_0030041 | Biological process | actin filament polymerization |
| GO_0001556 | Biological process | oocyte maturation |
| GO_0016197 | Biological process | endosomal transport |
| GO_0007032 | Biological process | endosome organization |
| GO_0090306 | Biological process | meiotic spindle assembly |
| GO_0015031 | Biological process | protein transport |
| GO_0034315 | Biological process | regulation of Arp2/3 complex-mediated actin nucleation |
| GO_0040038 | Biological process | polar body extrusion after meiotic divisions |
| GO_0031503 | Biological process | protein-containing complex localization |
| GO_0140285 | Biological process | endosome fission |
| GO_0005769 | Cellular component | early endosome |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0071203 | Cellular component | WASH complex |
| GO_0005768 | Cellular component | endosome |
| GO_0005515 | Molecular function | protein binding |
| Gene name | WASHC5 |
| Protein name | WASH complex subunit 5 (Strumpellin) (WASH complex subunit strumpellin) WASH complex subunit 5 (WASH complex subunit strumpellin) |
| Synonyms | KIAA0196 |
| Description | FUNCTION: Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting . May be involved in axonal outgrowth. Involved in cellular localization of ADRB2 . Involved in cellular trafficking of BLOC-1 complex cargos such as ATP7A and VAMP7 . . |
| Accessions | ENST00000318410.12 E7EQI7 ENST00000517845.5 ENST00000523297.5 Q12768 E5RFU6 |
