AP3S2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AP3S2 at tissue level.

III. Associated gene sets

GO_0008089Biological processanterograde axonal transport
GO_0036465Biological processsynaptic vesicle recycling
GO_0006896Biological processGolgi to vacuole transport
GO_0048490Biological processanterograde synaptic vesicle transport
GO_1903232Biological processmelanosome assembly
GO_0016192Biological processvesicle-mediated transport
GO_0035654Biological processclathrin-coated vesicle cargo loading, AP-3-mediated
GO_0006886Biological processintracellular protein transport
GO_0046907Biological processintracellular transport
GO_0060155Biological processplatelet dense granule organization
GO_0016183Biological processsynaptic vesicle coating
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0098793Cellular componentpresynapse
GO_0005794Cellular componentGolgi apparatus
GO_0030123Cellular componentAP-3 adaptor complex
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_1904115Cellular componentaxon cytoplasm
GO_0005769Cellular componentearly endosome

IV. Literature review

[source]
Gene nameAP3S2
Protein nameAdaptor related protein complex 3 subunit sigma 2 (Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_d)
AP complex subunit sigma
AP3S2 protein
AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adaptor-related protein complex 3 subunit sigma-2) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b)
Adaptor related protein complex 3 subunit sigma 2
SynonymshCG_27218
DescriptionFUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

AccessionsP59780
ENST00000336418.9 [P59780-1]
ENST00000558806.5
H0YLI7
ENST00000558999.5
H0YN38
ENST00000560251.1 [P59780-2]
ENST00000558011.5
ENST00000560940.5
A0A087WY05
H0YKM3
ENST00000423566.6 [P59780-2]
H0YNI6
Q6PK37
H0YLX6
ENST00000617003.1
ENST00000557999.5