Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 21 studies | 28% ± 9% | |
| macrophage | 15 studies | 25% ± 8% | |
| fibroblast | 15 studies | 27% ± 11% | |
| pericyte | 13 studies | 26% ± 8% | |
| smooth muscle cell | 12 studies | 25% ± 9% | |
| classical monocyte | 10 studies | 28% ± 10% | |
| endothelial cell of vascular tree | 8 studies | 26% ± 7% | |
| oligodendrocyte | 8 studies | 25% ± 8% | |
| epithelial cell | 7 studies | 39% ± 20% | |
| B cell | 6 studies | 30% ± 7% | |
| dendritic cell | 6 studies | 30% ± 15% | |
| mast cell | 6 studies | 30% ± 9% | |
| monocyte | 6 studies | 20% ± 4% | |
| myeloid cell | 6 studies | 27% ± 12% | |
| natural killer cell | 5 studies | 22% ± 4% | |
| endothelial cell of lymphatic vessel | 5 studies | 23% ± 3% | |
| naive B cell | 5 studies | 20% ± 5% | |
| non-classical monocyte | 5 studies | 32% ± 12% | |
| conventional dendritic cell | 5 studies | 27% ± 14% | |
| basal cell | 5 studies | 28% ± 9% | |
| type I pneumocyte | 4 studies | 21% ± 2% | |
| leukocyte | 4 studies | 23% ± 6% | |
| mononuclear phagocyte | 4 studies | 24% ± 3% | |
| CD4-positive, alpha-beta T cell | 4 studies | 23% ± 8% | |
| mature NK T cell | 4 studies | 19% ± 4% | |
| neutrophil | 4 studies | 20% ± 3% | |
| cardiac muscle cell | 4 studies | 20% ± 2% | |
| GABAergic neuron | 4 studies | 40% ± 15% | |
| oligodendrocyte precursor cell | 4 studies | 28% ± 11% | |
| microglial cell | 4 studies | 21% ± 5% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 23% ± 3% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 26% ± 6% | |
| hematopoietic precursor cell | 3 studies | 26% ± 13% | |
| glomerular endothelial cell | 3 studies | 20% ± 1% | |
| neuron | 3 studies | 28% ± 10% | |
| club cell | 3 studies | 22% ± 5% | |
| retina horizontal cell | 3 studies | 20% ± 2% | |
| retinal pigment epithelial cell | 3 studies | 35% ± 16% | |
| endothelial cell of artery | 3 studies | 22% ± 8% | |
| vein endothelial cell | 3 studies | 27% ± 8% | |
| ciliated cell | 3 studies | 27% ± 10% | |
| lymphocyte | 3 studies | 27% ± 4% | |
| gamma-delta T cell | 3 studies | 29% ± 4% | |
| regulatory T cell | 3 studies | 22% ± 4% | |
| glutamatergic neuron | 3 studies | 54% ± 8% | |
| pancreatic A cell | 3 studies | 27% ± 3% | |
| myofibroblast cell | 3 studies | 25% ± 2% | |
| goblet cell | 3 studies | 25% ± 12% | |
| astrocyte | 3 studies | 31% ± 4% | |
| interneuron | 3 studies | 42% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 4738.40 | 459 / 459 | 100% | 18.30 | 1118 / 1118 |
| esophagus | 100% | 4647.41 | 1445 / 1445 | 100% | 20.22 | 183 / 183 |
| kidney | 100% | 3776.83 | 89 / 89 | 100% | 23.35 | 901 / 901 |
| lung | 100% | 5632.92 | 578 / 578 | 100% | 16.17 | 1155 / 1155 |
| brain | 100% | 3738.03 | 2640 / 2642 | 100% | 17.21 | 705 / 705 |
| prostate | 100% | 4060.53 | 245 / 245 | 100% | 17.19 | 501 / 502 |
| uterus | 100% | 4412.82 | 170 / 170 | 100% | 16.22 | 458 / 459 |
| ovary | 100% | 4304.34 | 180 / 180 | 100% | 12.04 | 429 / 430 |
| adrenal gland | 100% | 4807.43 | 258 / 258 | 100% | 21.56 | 229 / 230 |
| bladder | 100% | 4577.10 | 21 / 21 | 99% | 14.18 | 501 / 504 |
| thymus | 100% | 4178.35 | 652 / 653 | 100% | 18.89 | 602 / 605 |
| stomach | 100% | 3086.25 | 359 / 359 | 99% | 14.09 | 283 / 286 |
| intestine | 100% | 4063.55 | 966 / 966 | 99% | 13.06 | 521 / 527 |
| liver | 100% | 2345.38 | 226 / 226 | 98% | 8.79 | 396 / 406 |
| skin | 100% | 4712.44 | 1808 / 1809 | 95% | 12.25 | 449 / 472 |
| pancreas | 95% | 1562.28 | 310 / 328 | 98% | 14.57 | 175 / 178 |
| adipose | 100% | 5094.07 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 7798.68 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 14.76 | 29 / 29 |
| muscle | 100% | 7347.21 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3197.78 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 19.53 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.57 | 1 / 1 |
| heart | 98% | 5505.65 | 848 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 2765.08 | 842 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 83% | 6.36 | 66 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030516 | Biological process | regulation of axon extension |
| GO_0008089 | Biological process | anterograde axonal transport |
| GO_2000643 | Biological process | positive regulation of early endosome to late endosome transport |
| GO_0032482 | Biological process | Rab protein signal transduction |
| GO_0006886 | Biological process | intracellular protein transport |
| GO_0017157 | Biological process | regulation of exocytosis |
| GO_0048260 | Biological process | positive regulation of receptor-mediated endocytosis |
| GO_0050775 | Biological process | positive regulation of dendrite morphogenesis |
| GO_0050821 | Biological process | protein stabilization |
| GO_0012506 | Cellular component | vesicle membrane |
| GO_0012505 | Cellular component | endomembrane system |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005769 | Cellular component | early endosome |
| GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0098559 | Cellular component | cytoplasmic side of early endosome membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005802 | Cellular component | trans-Golgi network |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0045202 | Cellular component | synapse |
| GO_0032154 | Cellular component | cleavage furrow |
| GO_0005768 | Cellular component | endosome |
| GO_0032580 | Cellular component | Golgi cisterna membrane |
| GO_1904115 | Cellular component | axon cytoplasm |
| GO_0019003 | Molecular function | GDP binding |
| GO_0005525 | Molecular function | GTP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | RAB21 |
| Protein name | Ras-related protein Rab-21 |
| Synonyms | KIAA0118 |
| Description | FUNCTION: Small GTPase involved in membrane trafficking control . During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis . Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity). As a result, may regulate cell adhesion and migration (By similarity). Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion . Modulates protein levels of the cargo receptors TMED2 and TMED10, and required for appropriate Golgi localization of TMED10 . . |
| Accessions | ENST00000261263.5 Q9UL25 |