Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 7871.77 | 652 / 653 | 100% | 73.31 | 604 / 605 |
| breast | 100% | 4660.64 | 458 / 459 | 98% | 25.42 | 1092 / 1118 |
| lung | 100% | 6507.29 | 578 / 578 | 95% | 30.48 | 1093 / 1155 |
| ovary | 100% | 4030.08 | 180 / 180 | 89% | 16.58 | 383 / 430 |
| bladder | 95% | 2446.52 | 20 / 21 | 86% | 19.88 | 434 / 504 |
| skin | 95% | 3005.30 | 1714 / 1809 | 86% | 20.11 | 408 / 472 |
| uterus | 99% | 4409.18 | 169 / 170 | 81% | 20.17 | 371 / 459 |
| intestine | 94% | 2159.03 | 911 / 966 | 86% | 17.63 | 451 / 527 |
| kidney | 98% | 2320.15 | 87 / 89 | 78% | 29.56 | 706 / 901 |
| liver | 88% | 1468.88 | 199 / 226 | 81% | 22.67 | 330 / 406 |
| prostate | 91% | 2350.61 | 224 / 245 | 76% | 10.49 | 382 / 502 |
| esophagus | 84% | 3462.58 | 1218 / 1445 | 83% | 13.87 | 151 / 183 |
| stomach | 73% | 1171.98 | 262 / 359 | 87% | 20.29 | 250 / 286 |
| brain | 54% | 993.96 | 1414 / 2642 | 96% | 29.37 | 677 / 705 |
| adrenal gland | 67% | 877.53 | 173 / 258 | 70% | 15.05 | 162 / 230 |
| pancreas | 5% | 60.81 | 16 / 328 | 96% | 31.79 | 170 / 178 |
| adipose | 100% | 6695.62 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 236.00 | 29 / 29 |
| spleen | 100% | 5647.05 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.42 | 1 / 1 |
| heart | 99% | 2857.42 | 856 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 5252.70 | 1324 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 23.63 | 41 / 45 |
| muscle | 80% | 1260.37 | 646 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 66% | 5087.33 | 611 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 28% | 3.11 | 22 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0040010 | Biological process | positive regulation of growth rate |
| GO_0001765 | Biological process | membrane raft assembly |
| GO_0043330 | Biological process | response to exogenous dsRNA |
| GO_0034138 | Biological process | toll-like receptor 3 signaling pathway |
| GO_0050853 | Biological process | B cell receptor signaling pathway |
| GO_1903044 | Biological process | protein localization to membrane raft |
| GO_0050852 | Biological process | T cell receptor signaling pathway |
| GO_0002457 | Biological process | T cell antigen processing and presentation |
| GO_0032596 | Biological process | protein transport into membrane raft |
| GO_0033227 | Biological process | dsRNA transport |
| GO_0032740 | Biological process | positive regulation of interleukin-17 production |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045121 | Cellular component | membrane raft |
| GO_0005769 | Cellular component | early endosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005768 | Cellular component | endosome |
| GO_0003725 | Molecular function | double-stranded RNA binding |
| Gene name | RFTN1 |
| Protein name | Raftlin (Cell migration-inducing gene 2 protein) (Raft-linking protein) RFTN1 protein Raft-linking protein, isoform CRA_c (Raftlin, lipid raft linker 1) Raftlin, lipid raft linker 1 |
| Synonyms | hCG_27653 KIAA0084 RAFTLIN MIG2 |
| Description | FUNCTION: Involved in protein trafficking via association with clathrin and AP2 complex . Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production . Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling . May play a pivotal role in the formation and/or maintenance of lipid rafts . . |
| Accessions | G3XAJ6 Q8N5I0 Q9BRA3 ENST00000449415.5 ENST00000453536.5 ENST00000431547.1 ENST00000432519.5 Q14699 U3KPZ2 ENST00000334133.9 C9JHG2 ENST00000441460.5 C9JWQ9 ENST00000607320.5 C9JRN3 F8WAR1 ENST00000451036.5 |
