I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 17% ± 1% |
Insufficient scRNA-seq data for expression of MICALL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 6097.31 | 1442 / 1445 | 100% | 80.85 | 183 / 183 |
| skin | 100% | 5946.17 | 1809 / 1809 | 100% | 51.66 | 471 / 472 |
| intestine | 100% | 5520.66 | 965 / 966 | 99% | 22.55 | 521 / 527 |
| bladder | 100% | 5410.29 | 21 / 21 | 99% | 51.32 | 497 / 504 |
| uterus | 100% | 4676.29 | 170 / 170 | 98% | 65.08 | 452 / 459 |
| thymus | 100% | 2451.97 | 652 / 653 | 99% | 23.37 | 596 / 605 |
| stomach | 100% | 6920.86 | 359 / 359 | 98% | 24.20 | 280 / 286 |
| prostate | 100% | 4094.27 | 245 / 245 | 98% | 20.75 | 491 / 502 |
| pancreas | 99% | 2101.91 | 326 / 328 | 98% | 26.39 | 174 / 178 |
| lung | 99% | 2581.22 | 575 / 578 | 97% | 42.56 | 1126 / 1155 |
| breast | 100% | 2347.15 | 457 / 459 | 97% | 24.96 | 1085 / 1118 |
| kidney | 99% | 1679.40 | 88 / 89 | 92% | 16.05 | 832 / 901 |
| ovary | 72% | 869.41 | 130 / 180 | 95% | 21.38 | 410 / 430 |
| brain | 65% | 949.76 | 1721 / 2642 | 98% | 22.51 | 688 / 705 |
| adrenal gland | 97% | 1199.35 | 250 / 258 | 64% | 7.75 | 148 / 230 |
| liver | 56% | 668.71 | 127 / 226 | 67% | 9.77 | 270 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 35.95 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 24.13 | 29 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 83.05 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 28.99 | 1 / 1 |
| adipose | 99% | 1885.30 | 1193 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 2079.59 | 1308 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 98% | 1555.92 | 235 / 241 | 0% | 0 | 0 / 0 |
| muscle | 88% | 1202.39 | 706 / 803 | 0% | 0 | 0 / 0 |
| heart | 83% | 1004.08 | 713 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 56% | 775.34 | 517 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032458 | Biological process | slow endocytic recycling |
| GO_0006897 | Biological process | endocytosis |
| GO_0006898 | Biological process | receptor-mediated endocytosis |
| GO_0031175 | Biological process | neuron projection development |
| GO_0006612 | Biological process | protein targeting to membrane |
| GO_0097320 | Biological process | plasma membrane tubulation |
| GO_0032456 | Biological process | endocytic recycling |
| GO_0015031 | Biological process | protein transport |
| GO_0036010 | Biological process | protein localization to endosome |
| GO_0031902 | Cellular component | late endosome membrane |
| GO_0005769 | Cellular component | early endosome |
| GO_0055038 | Cellular component | recycling endosome membrane |
| GO_0005802 | Cellular component | trans-Golgi network |
| GO_0010009 | Cellular component | cytoplasmic side of endosome membrane |
| GO_0005770 | Cellular component | late endosome |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0031267 | Molecular function | small GTPase binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0070300 | Molecular function | phosphatidic acid binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MICALL1 |
| Protein name | MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13) MICAL like 1 |
| Synonyms | MIRAB13 KIAA1668 |
| Description | FUNCTION: Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth. . |
| Accessions | A0A7P0T9P2 ENST00000454685.6 ENST00000445494.6 ENST00000680375.1 Q8N3F8 ENST00000681920.1 ENST00000680501.1 B0QY91 ENST00000680578.1 A0A7P0T7Z5 ENST00000424008.2 A0A7P0T8A6 A0A7P0Z427 ENST00000215957.10 H0Y6J8 B0QY86 ENST00000679832.1 A0A7P0Z4L3 |
