NEURL1B report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NEURL1B at tissue level.

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0007219Biological processNotch signaling pathway
GO_0070086Biological processubiquitin-dependent endocytosis
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0005769Cellular componentearly endosome
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameNEURL1B
Protein nameE3 ubiquitin-protein ligase NEURL1B (EC 2.3.2.27) (Neuralized-2) (NEUR2) (Neuralized-like protein 1B) (Neuralized-like protein 3) (RING-type E3 ubiquitin transferase NEURL1B)
SynonymsNEURL3
DescriptionFUNCTION: E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands. .

AccessionsENST00000520919.5 [A8MQ27-3]
A8MQ27
ENST00000369800.6 [A8MQ27-1]
ENST00000522853.5 [A8MQ27-2]