Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 11 studies | 23% ± 6% | |
pericyte | 11 studies | 27% ± 10% | |
smooth muscle cell | 8 studies | 23% ± 5% | |
capillary endothelial cell | 6 studies | 21% ± 3% | |
vein endothelial cell | 5 studies | 30% ± 19% | |
fibroblast | 5 studies | 26% ± 14% | |
endothelial cell of vascular tree | 4 studies | 22% ± 2% | |
glutamatergic neuron | 3 studies | 25% ± 8% |
Insufficient scRNA-seq data for expression of NEURL1B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 5868.14 | 459 / 459 | 99% | 23.05 | 1104 / 1118 |
intestine | 100% | 6582.50 | 966 / 966 | 98% | 22.93 | 517 / 527 |
uterus | 100% | 6707.39 | 170 / 170 | 98% | 37.14 | 450 / 459 |
esophagus | 100% | 4829.76 | 1445 / 1445 | 97% | 26.47 | 177 / 183 |
prostate | 100% | 4984.81 | 244 / 245 | 95% | 13.71 | 476 / 502 |
ovary | 99% | 3882.61 | 178 / 180 | 94% | 19.44 | 406 / 430 |
adrenal gland | 99% | 4222.74 | 256 / 258 | 94% | 17.18 | 216 / 230 |
lung | 99% | 3435.06 | 574 / 578 | 93% | 19.39 | 1075 / 1155 |
thymus | 99% | 3013.28 | 648 / 653 | 92% | 11.61 | 557 / 605 |
bladder | 100% | 6848.67 | 21 / 21 | 85% | 16.40 | 430 / 504 |
stomach | 76% | 1679.14 | 273 / 359 | 95% | 24.45 | 272 / 286 |
kidney | 91% | 2281.08 | 81 / 89 | 75% | 19.90 | 679 / 901 |
pancreas | 51% | 601.47 | 168 / 328 | 96% | 19.75 | 170 / 178 |
brain | 50% | 929.05 | 1313 / 2642 | 97% | 18.51 | 682 / 705 |
skin | 72% | 2235.26 | 1306 / 1809 | 65% | 5.88 | 307 / 472 |
liver | 43% | 619.49 | 98 / 226 | 76% | 7.98 | 310 / 406 |
adipose | 100% | 6778.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 57.43 | 45 / 45 |
heart | 99% | 3726.09 | 856 / 861 | 0% | 0 | 0 / 0 |
muscle | 97% | 1953.02 | 782 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 88% | 2832.99 | 1181 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 2.14 | 10 / 29 |
eye | 0% | 0 | 0 / 0 | 24% | 1.34 | 19 / 80 |
spleen | 1% | 17.44 | 3 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0016567 | Biological process | protein ubiquitination |
GO_0007219 | Biological process | Notch signaling pathway |
GO_0070086 | Biological process | ubiquitin-dependent endocytosis |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005769 | Cellular component | early endosome |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | NEURL1B |
Protein name | E3 ubiquitin-protein ligase NEURL1B (EC 2.3.2.27) (Neuralized-2) (NEUR2) (Neuralized-like protein 1B) (Neuralized-like protein 3) (RING-type E3 ubiquitin transferase NEURL1B) |
Synonyms | NEURL3 |
Description | FUNCTION: E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands. . |
Accessions | ENST00000520919.5 [A8MQ27-3] A8MQ27 ENST00000369800.6 [A8MQ27-1] ENST00000522853.5 [A8MQ27-2] |