MELTF report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MELTF at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MELTF at tissue level.

III. Associated gene sets

GO_1900025Biological processnegative regulation of substrate adhesion-dependent cell spreading
GO_0090091Biological processpositive regulation of extracellular matrix disassembly
GO_0006826Biological processiron ion transport
GO_0001558Biological processregulation of cell growth
GO_0010756Biological processpositive regulation of plasminogen activation
GO_0042127Biological processregulation of cell population proliferation
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0098552Cellular componentside of membrane
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0055037Cellular componentrecycling endosome
GO_0005769Cellular componentearly endosome
GO_0005506Molecular functioniron ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMELTF
Protein nameMelanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228)
Melanotransferrin
Antigen p97 (Melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 (Melanoma-associated antigen p97, isoform 2)
SynonymsMFI2
hCG_41190
MAP97
DescriptionFUNCTION: Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. .

AccessionsC9JVN1
ENST00000296350.10 [P08582-1]
Q53XS6
ENST00000696016.1
A0A8Q3WLY9
P08582
ENST00000439320.1
ENST00000296351.8 [P08582-2]