Insufficient scRNA-seq data for expression of MELTF at single-cell level.
Insufficient scRNA-seq data for expression of MELTF at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 98% | 2132.98 | 1770 / 1809 | 89% | 97.00 | 422 / 472 |
| intestine | 98% | 763.73 | 950 / 966 | 89% | 22.48 | 468 / 527 |
| uterus | 100% | 995.25 | 170 / 170 | 86% | 22.14 | 394 / 459 |
| pancreas | 95% | 467.96 | 312 / 328 | 90% | 30.27 | 160 / 178 |
| esophagus | 99% | 512.01 | 1427 / 1445 | 82% | 21.51 | 150 / 183 |
| thymus | 99% | 607.64 | 648 / 653 | 80% | 10.85 | 487 / 605 |
| breast | 100% | 1423.77 | 458 / 459 | 65% | 12.96 | 728 / 1118 |
| bladder | 100% | 563.52 | 21 / 21 | 60% | 16.46 | 303 / 504 |
| lung | 79% | 304.79 | 458 / 578 | 71% | 16.75 | 815 / 1155 |
| ovary | 70% | 220.52 | 126 / 180 | 76% | 10.08 | 328 / 430 |
| stomach | 62% | 207.09 | 221 / 359 | 78% | 14.82 | 222 / 286 |
| prostate | 99% | 811.51 | 243 / 245 | 26% | 1.46 | 131 / 502 |
| brain | 91% | 494.85 | 2413 / 2642 | 25% | 1.75 | 176 / 705 |
| adipose | 99% | 1167.36 | 1190 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 21.58 | 79 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 29.27 | 43 / 45 |
| heart | 93% | 617.21 | 804 / 861 | 0% | 0 | 0 / 0 |
| kidney | 74% | 1085.73 | 66 / 89 | 16% | 2.32 | 140 / 901 |
| adrenal gland | 18% | 70.94 | 46 / 258 | 55% | 14.39 | 126 / 230 |
| blood vessel | 56% | 217.47 | 742 / 1335 | 0% | 0 | 0 / 0 |
| liver | 23% | 102.38 | 51 / 226 | 31% | 6.52 | 124 / 406 |
| spleen | 37% | 83.69 | 89 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 2.93 | 9 / 29 |
| peripheral blood | 22% | 552.96 | 209 / 929 | 0% | 0 | 0 / 0 |
| muscle | 7% | 16.91 | 56 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1900025 | Biological process | negative regulation of substrate adhesion-dependent cell spreading |
| GO_0090091 | Biological process | positive regulation of extracellular matrix disassembly |
| GO_0006826 | Biological process | iron ion transport |
| GO_0001558 | Biological process | regulation of cell growth |
| GO_0010756 | Biological process | positive regulation of plasminogen activation |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0009986 | Cellular component | cell surface |
| GO_0098552 | Cellular component | side of membrane |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0055037 | Cellular component | recycling endosome |
| GO_0005769 | Cellular component | early endosome |
| GO_0005506 | Molecular function | iron ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MELTF |
| Protein name | Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228) Melanotransferrin Antigen p97 (Melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 (Melanoma-associated antigen p97, isoform 2) |
| Synonyms | MFI2 hCG_41190 MAP97 |
| Description | FUNCTION: Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. . |
| Accessions | C9JVN1 ENST00000296350.10 [P08582-1] Q53XS6 ENST00000696016.1 A0A8Q3WLY9 P08582 ENST00000439320.1 ENST00000296351.8 [P08582-2] |