Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 17 studies | 40% ± 20% | |
macrophage | 15 studies | 38% ± 19% | |
oligodendrocyte | 14 studies | 47% ± 17% | |
mast cell | 13 studies | 30% ± 11% | |
oligodendrocyte precursor cell | 12 studies | 35% ± 18% | |
endothelial cell | 11 studies | 30% ± 14% | |
microglial cell | 11 studies | 46% ± 13% | |
dendritic cell | 10 studies | 33% ± 14% | |
myeloid cell | 9 studies | 30% ± 11% | |
classical monocyte | 8 studies | 26% ± 13% | |
GABAergic neuron | 8 studies | 33% ± 18% | |
plasmacytoid dendritic cell | 8 studies | 27% ± 9% | |
adipocyte | 8 studies | 27% ± 8% | |
fibroblast | 8 studies | 27% ± 12% | |
glutamatergic neuron | 7 studies | 41% ± 23% | |
B cell | 7 studies | 25% ± 8% | |
non-classical monocyte | 6 studies | 29% ± 12% | |
pericyte | 6 studies | 30% ± 11% | |
endothelial cell of lymphatic vessel | 6 studies | 34% ± 16% | |
monocyte | 6 studies | 38% ± 13% | |
interneuron | 5 studies | 39% ± 26% | |
naive B cell | 5 studies | 19% ± 3% | |
smooth muscle cell | 5 studies | 22% ± 6% | |
Mueller cell | 5 studies | 31% ± 9% | |
type I pneumocyte | 5 studies | 27% ± 8% | |
type II pneumocyte | 5 studies | 18% ± 5% | |
hematopoietic precursor cell | 4 studies | 27% ± 7% | |
granule cell | 4 studies | 27% ± 11% | |
neuron | 4 studies | 49% ± 16% | |
epithelial cell | 4 studies | 40% ± 23% | |
ciliated cell | 4 studies | 27% ± 10% | |
club cell | 4 studies | 23% ± 9% | |
lymphocyte | 3 studies | 25% ± 8% | |
retina horizontal cell | 3 studies | 23% ± 7% | |
retinal rod cell | 3 studies | 18% ± 2% | |
hepatocyte | 3 studies | 43% ± 26% | |
ependymal cell | 3 studies | 40% ± 20% | |
T cell | 3 studies | 22% ± 2% | |
alveolar macrophage | 3 studies | 47% ± 12% | |
basal cell | 3 studies | 45% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2587.86 | 1443 / 1445 | 100% | 5.75 | 183 / 183 |
thymus | 100% | 3068.03 | 653 / 653 | 99% | 4.03 | 601 / 605 |
breast | 100% | 4003.66 | 459 / 459 | 99% | 3.49 | 1109 / 1118 |
brain | 99% | 1901.96 | 2623 / 2642 | 100% | 4.90 | 704 / 705 |
pancreas | 100% | 4604.30 | 328 / 328 | 99% | 2.71 | 176 / 178 |
adrenal gland | 100% | 5005.95 | 258 / 258 | 98% | 3.87 | 225 / 230 |
lung | 100% | 2679.81 | 576 / 578 | 97% | 3.83 | 1124 / 1155 |
uterus | 100% | 3030.27 | 170 / 170 | 97% | 3.55 | 444 / 459 |
skin | 100% | 6848.65 | 1809 / 1809 | 96% | 3.68 | 453 / 472 |
prostate | 100% | 2603.84 | 245 / 245 | 93% | 2.28 | 466 / 502 |
stomach | 100% | 2374.28 | 359 / 359 | 93% | 2.24 | 265 / 286 |
bladder | 100% | 2108.33 | 21 / 21 | 92% | 2.56 | 463 / 504 |
ovary | 100% | 3740.26 | 180 / 180 | 87% | 2.41 | 375 / 430 |
intestine | 98% | 1759.76 | 948 / 966 | 88% | 1.92 | 464 / 527 |
kidney | 100% | 1800.62 | 89 / 89 | 76% | 1.84 | 684 / 901 |
liver | 100% | 1641.42 | 226 / 226 | 60% | 1.11 | 243 / 406 |
adipose | 100% | 3082.84 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 3590.73 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 4.01 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.02 | 1 / 1 |
blood vessel | 99% | 2141.90 | 1325 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 2702.05 | 907 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 2.62 | 28 / 29 |
heart | 92% | 1144.12 | 792 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 76% | 1.58 | 61 / 80 |
muscle | 25% | 193.80 | 197 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0045600 | Biological process | positive regulation of fat cell differentiation |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0031982 | Cellular component | vesicle |
GO_0005769 | Cellular component | early endosome |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | WDFY2 |
Protein name | WD repeat and FYVE domain containing 2 WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22) |
Synonyms | ZFYVE22 WDF2 |
Description | FUNCTION: Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 . Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 . Plays a role in endosomal control of AKT2 signaling; required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis . . |
Accessions | ENST00000612477.1 ENST00000298125.7 A0A087WZX3 Q96P53 |