AP3M2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008089Biological processanterograde axonal transport
GO_0036465Biological processsynaptic vesicle recycling
GO_0048490Biological processanterograde synaptic vesicle transport
GO_0006886Biological processintracellular protein transport
GO_0035654Biological processclathrin-coated vesicle cargo loading, AP-3-mediated
GO_0046907Biological processintracellular transport
GO_0006897Biological processendocytosis
GO_0016183Biological processsynaptic vesicle coating
GO_0030131Cellular componentclathrin adaptor complex
GO_0030119Cellular componentAP-type membrane coat adaptor complex
GO_0098793Cellular componentpresynapse
GO_0005794Cellular componentGolgi apparatus
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0030123Cellular componentAP-3 adaptor complex
GO_0031410Cellular componentcytoplasmic vesicle
GO_1904115Cellular componentaxon cytoplasm
GO_0005769Cellular componentearly endosome

IV. Literature review

[source]
Gene nameAP3M2
Protein nameAdaptor related protein complex 3 subunit mu 2
AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B)
Synonyms
DescriptionFUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

AccessionsA0A1D5RMS9
ENST00000518421.5 [P53677-1]
ENST00000517969.1
E5RJ52
H0YAY4
ENST00000521280.5
ENST00000517865.5
ENST00000520689.1
ENST00000517499.5
ENST00000396926.8 [P53677-1]
ENST00000522288.5
ENST00000530375.5 [P53677-2]
ENST00000517922.5
ENST00000522606.5
P53677
E7ER80
E5RGF3
H0YBA0
E5RI83
H0YBM0