RAB14 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046907Biological processintracellular transport
GO_0045995Biological processregulation of embryonic development
GO_0090382Biological processphagosome maturation
GO_0034498Biological processearly endosome to Golgi transport
GO_0032880Biological processregulation of protein localization
GO_0006886Biological processintracellular protein transport
GO_0032456Biological processendocytic recycling
GO_0090387Biological processphagolysosome assembly involved in apoptotic cell clearance
GO_0016192Biological processvesicle-mediated transport
GO_0042742Biological processdefense response to bacterium
GO_0034058Biological processendosomal vesicle fusion
GO_0008543Biological processfibroblast growth factor receptor signaling pathway
GO_0006895Biological processGolgi to endosome transport
GO_0005795Cellular componentGolgi stack
GO_0005886Cellular componentplasma membrane
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0012505Cellular componentendomembrane system
GO_0055037Cellular componentrecycling endosome
GO_0005769Cellular componentearly endosome
GO_0031901Cellular componentearly endosome membrane
GO_0005764Cellular componentlysosome
GO_0070062Cellular componentextracellular exosome
GO_0055038Cellular componentrecycling endosome membrane
GO_0042175Cellular componentnuclear outer membrane-endoplasmic reticulum membrane network
GO_0005802Cellular componenttrans-Golgi network
GO_0000139Cellular componentGolgi membrane
GO_0005929Cellular componentcilium
GO_0005829Cellular componentcytosol
GO_0045335Cellular componentphagocytic vesicle
GO_0070821Cellular componenttertiary granule membrane
GO_0030140Cellular componenttrans-Golgi network transport vesicle
GO_0005770Cellular componentlate endosome
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005791Cellular componentrough endoplasmic reticulum
GO_0005765Cellular componentlysosomal membrane
GO_0019003Molecular functionGDP binding
GO_0031489Molecular functionmyosin V binding
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAB14
Protein nameRas-related protein Rab-14
RAB14, member RAS oncogene family
Synonyms
DescriptionFUNCTION: Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion. .

AccessionsENST00000451303.1
A0A994J451
ENST00000704000.1
ENST00000703998.1
ENST00000703997.1
X6RFL8
A0A994J4B9
A0A994J774
P61106
ENST00000703996.1
ENST00000373840.9
ENST00000703999.1