AP1G1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035646Biological processendosome to melanosome transport
GO_0016182Biological processsynaptic vesicle budding from endosome
GO_0045954Biological processpositive regulation of natural killer cell mediated cytotoxicity
GO_0043323Biological processpositive regulation of natural killer cell degranulation
GO_0048488Biological processsynaptic vesicle endocytosis
GO_0006886Biological processintracellular protein transport
GO_0032438Biological processmelanosome organization
GO_0016192Biological processvesicle-mediated transport
GO_0060155Biological processplatelet dense granule organization
GO_0090160Biological processGolgi to lysosome transport
GO_0110010Biological processbasolateral protein secretion
GO_0006896Biological processGolgi to vacuole transport
GO_1903232Biological processmelanosome assembly
GO_0098793Cellular componentpresynapse
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0016020Cellular componentmembrane
GO_0055037Cellular componentrecycling endosome
GO_0005769Cellular componentearly endosome
GO_0030121Cellular componentAP-1 adaptor complex
GO_0030136Cellular componentclathrin-coated vesicle
GO_0005794Cellular componentGolgi apparatus
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005905Cellular componentclathrin-coated pit
GO_0030665Cellular componentclathrin-coated vesicle membrane
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0005765Cellular componentlysosomal membrane
GO_0030742Molecular functionGTP-dependent protein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0035615Molecular functionclathrin adaptor activity
GO_0005518Molecular functioncollagen binding
GO_0005515Molecular functionprotein binding
GO_0019894Molecular functionkinesin binding

IV. Literature review

[source]
Gene nameAP1G1
Protein nameAdaptor related protein complex 1 subunit gamma 1
AP1G1 protein
Adaptor related protein complex 1 subunit gamma 1 (cDNA FLJ30560 fis, clone BRAWH2004217, highly similar to AP-1 complex subunit gamma-1)
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
AP-1 complex subunit gamma
SynonymsADTG
CLAPG1
DescriptionFUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes . .

AccessionsH3BNN2
ENST00000565412.5
ENST00000299980.9 [O43747-1]
ENST00000569748.5 [O43747-1]
O43747
H3BS13
H3BN75
H3BPN9
ENST00000568327.5
ENST00000566179.1
H3BR36
ENST00000565009.5
ENST00000393512.7 [O43747-2]
ENST00000570017.1
ENST00000450149.6
H3BV30
H3BRM7
ENST00000569975.5
Q8IY97
H3BN71
B3KNW1
ENST00000563104.5
Q9BTR5
ENST00000564155.5
H3BUN9
B4DGE1
H3BNR4
ENST00000569185.5
ENST00000563259.5
ENST00000567583.1