AP3B2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008089Biological processanterograde axonal transport
GO_0036465Biological processsynaptic vesicle recycling
GO_0048490Biological processanterograde synaptic vesicle transport
GO_0016192Biological processvesicle-mediated transport
GO_0035654Biological processclathrin-coated vesicle cargo loading, AP-3-mediated
GO_0006886Biological processintracellular protein transport
GO_0046907Biological processintracellular transport
GO_0016183Biological processsynaptic vesicle coating
GO_0097708Cellular componentintracellular vesicle
GO_0098793Cellular componentpresynapse
GO_0005794Cellular componentGolgi apparatus
GO_0030123Cellular componentAP-3 adaptor complex
GO_0030665Cellular componentclathrin-coated vesicle membrane
GO_1904115Cellular componentaxon cytoplasm
GO_0005769Cellular componentearly endosome

IV. Literature review

[source]
Gene nameAP3B2
Protein nameAP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP)
AP complex subunit beta
AP-3 complex subunit beta
Adaptor related protein complex 3 subunit beta 2
Synonyms
DescriptionFUNCTION: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

FUNCTION: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

FUNCTION: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

FUNCTION: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

FUNCTION: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

FUNCTION: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. .

AccessionsA0A590UJW5
ENST00000535513.2
ENST00000541693.5
A0A590UKD3
A0A590UJ88
A0A590UK04
ENST00000661532.1
ENST00000660624.1
ENST00000535359.6 [Q13367-4]
A0A590UK30
A0A590UJU0
A0A2R8Y2A8
ENST00000666055.1
A0A590UKC4
ENST00000681327.1
ENST00000665513.1
A0A590UJS5
A0A590UJU7
ENST00000535348.5 [Q13367-3]
ENST00000669930.1
A0A590UJE5
ENST00000666973.1
ENST00000652847.1
A0A590UJ44
ENST00000657321.1
ENST00000668385.1
ENST00000261722.8
ENST00000668458.1
Q13367
A0A590UJ60
ENST00000668990.2 [Q13367-1]
ENST00000542200.2
A0A590UK69
ENST00000642989.2
ENST00000666894.1
A0A5F9UJV3
ENST00000667758.1
A0A590UK64
ENST00000664460.1
F5GYB0
F5GWU4