RABGAP1L | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	34% ± 18%	Explore
B cell	25 studies	32% ± 19%	Explore
endothelial cell	24 studies	51% ± 15%	Explore
astrocyte	19 studies	45% ± 19%	Explore
T cell	18 studies	35% ± 22%	Explore
CD4-positive, alpha-beta T cell	18 studies	27% ± 17%	Explore
CD8-positive, alpha-beta T cell	18 studies	31% ± 17%	Explore
regulatory T cell	18 studies	31% ± 14%	Explore
non-classical monocyte	16 studies	33% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	31% ± 15%	Explore
macrophage	15 studies	44% ± 18%	Explore
oligodendrocyte	15 studies	53% ± 16%	Explore
oligodendrocyte precursor cell	15 studies	56% ± 18%	Explore
microglial cell	15 studies	59% ± 13%	Explore
ciliated cell	14 studies	42% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	36% ± 14%	Explore
mature NK T cell	13 studies	27% ± 14%	Explore
plasmacytoid dendritic cell	13 studies	33% ± 11%	Explore
memory B cell	12 studies	20% ± 4%	Explore
smooth muscle cell	12 studies	39% ± 14%	Explore
glutamatergic neuron	12 studies	80% ± 14%	Explore
fibroblast	12 studies	46% ± 12%	Explore
GABAergic neuron	11 studies	72% ± 20%	Explore
pericyte	11 studies	39% ± 16%	Explore
mucosal invariant T cell	11 studies	27% ± 14%	Explore
gamma-delta T cell	11 studies	23% ± 5%	Explore
type I pneumocyte	10 studies	41% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	28% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	31% ± 16%	Explore
monocyte	9 studies	40% ± 21%	Explore
platelet	9 studies	28% ± 10%	Explore
epithelial cell	9 studies	51% ± 20%	Explore
adipocyte	9 studies	35% ± 11%	Explore
endothelial cell of lymphatic vessel	9 studies	46% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	21% ± 4%	Explore
leukocyte	8 studies	46% ± 26%	Explore
classical monocyte	8 studies	20% ± 6%	Explore
myeloid cell	8 studies	43% ± 17%	Explore
basal cell	8 studies	37% ± 20%	Explore
type II pneumocyte	8 studies	48% ± 21%	Explore
dendritic cell	8 studies	50% ± 19%	Explore
mast cell	8 studies	37% ± 15%	Explore
neuron	7 studies	60% ± 23%	Explore
naive B cell	7 studies	21% ± 5%	Explore
club cell	7 studies	37% ± 16%	Explore
mesothelial cell	7 studies	45% ± 13%	Explore
interneuron	6 studies	78% ± 16%	Explore
cardiac muscle cell	6 studies	75% ± 16%	Explore
T follicular helper cell	6 studies	22% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
plasma cell	5 studies	53% ± 23%	Explore
retinal ganglion cell	5 studies	53% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	32% ± 20%	Explore
retinal cone cell	5 studies	64% ± 27%	Explore
innate lymphoid cell	5 studies	33% ± 20%	Explore
goblet cell	5 studies	33% ± 26%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	37% ± 22%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 6%	Explore
cholangiocyte	4 studies	54% ± 20%	Explore
hepatocyte	4 studies	62% ± 29%	Explore
differentiation-committed oligodendrocyte precursor	4 studies	44% ± 10%	Explore
granule cell	4 studies	76% ± 14%	Explore
progenitor cell	4 studies	32% ± 10%	Explore
retinal pigment epithelial cell	4 studies	65% ± 25%	Explore
mononuclear phagocyte	4 studies	33% ± 13%	Explore
vein endothelial cell	4 studies	33% ± 15%	Explore
lymphocyte	4 studies	64% ± 19%	Explore
Mueller cell	4 studies	48% ± 13%	Explore
OFF-bipolar cell	4 studies	44% ± 26%	Explore
amacrine cell	4 studies	52% ± 7%	Explore
retina horizontal cell	4 studies	45% ± 14%	Explore
retinal rod cell	4 studies	58% ± 17%	Explore
respiratory goblet cell	4 studies	47% ± 19%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	19% ± 4%	Explore
erythrocyte	4 studies	46% ± 20%	Explore
abnormal cell	4 studies	33% ± 22%	Explore
exhausted T cell	3 studies	29% ± 3%	Explore
plasmablast	3 studies	24% ± 11%	Explore
GABAergic interneuron	3 studies	77% ± 5%	Explore
glial cell	3 studies	40% ± 6%	Explore
megakaryocyte	3 studies	38% ± 10%	Explore
squamous epithelial cell	3 studies	41% ± 22%	Explore
endothelial cell of artery	3 studies	22% ± 4%	Explore
GABAergic amacrine cell	3 studies	57% ± 12%	Explore
ON-bipolar cell	3 studies	53% ± 24%	Explore
glycinergic amacrine cell	3 studies	50% ± 8%	Explore
germinal center B cell	3 studies	34% ± 9%	Explore
endothelial cell of vascular tree	3 studies	49% ± 11%	Explore
ependymal cell	3 studies	42% ± 16%	Explore
enteroendocrine cell	3 studies	26% ± 6%	Explore
alveolar macrophage	3 studies	63% ± 8%	Explore
capillary endothelial cell	3 studies	41% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	26% ± 7%	Explore
muscle cell	3 studies	32% ± 13%	Explore
brush cell	3 studies	28% ± 7%	Explore
double negative thymocyte	3 studies	25% ± 10%	Explore
mural cell	3 studies	56% ± 8%	Explore
mucus secreting cell	3 studies	53% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	63% ± 19%	Explore
peripheral blood	11 studies	21% ± 4%	Explore
lung	9 studies	37% ± 18%	Explore
liver	6 studies	32% ± 20%	Explore
heart	6 studies	47% ± 19%	Explore
eye	5 studies	56% ± 10%	Explore
kidney	5 studies	43% ± 19%	Explore
adipose	4 studies	38% ± 14%	Explore
intestine	3 studies	18% ± 0%	Explore
lymph node	3 studies	17% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3256.70	1445 / 1445	100%	13.25	183 / 183
brain	100%	3739.18	2638 / 2642	100%	11.26	705 / 705
lung	100%	2670.07	577 / 578	100%	12.45	1155 / 1155
breast	100%	2086.96	459 / 459	100%	13.62	1116 / 1118
bladder	100%	2125.10	21 / 21	100%	13.99	502 / 504
intestine	100%	2436.70	966 / 966	99%	10.56	523 / 527
pancreas	100%	1796.76	327 / 328	99%	14.48	177 / 178
uterus	100%	2138.43	170 / 170	99%	9.98	455 / 459
thymus	100%	1987.65	652 / 653	99%	7.55	599 / 605
stomach	100%	1667.48	359 / 359	98%	11.89	281 / 286
ovary	100%	2799.38	180 / 180	98%	5.98	420 / 430
prostate	100%	1734.91	245 / 245	97%	5.24	488 / 502
kidney	100%	1720.37	89 / 89	97%	6.17	870 / 901
skin	100%	2221.80	1808 / 1809	96%	7.56	451 / 472
adrenal gland	97%	980.88	250 / 258	93%	7.64	215 / 230
liver	93%	938.54	210 / 226	89%	4.85	363 / 406
lymph node	0%	0	0 / 0	100%	23.39	29 / 29
spleen	100%	3219.28	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	9.52	45 / 45
ureter	0%	0	0 / 0	100%	14.06	1 / 1
blood vessel	100%	2690.37	1334 / 1335	0%	0	0 / 0
adipose	100%	2081.97	1202 / 1204	0%	0	0 / 0
heart	98%	7429.34	845 / 861	0%	0	0 / 0
peripheral blood	97%	3487.50	901 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	84%	4.56	67 / 80
muscle	65%	538.07	520 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	RABGAP1L
Protein name	Rab GTPase-activating protein 1-like RAB GTPase activating protein 1 like Rab GTPase-activating protein 1-like, isoform 10
Synonyms	KIAA0471 HHL
Description	FUNCTION: GTP-hydrolysis activating protein (GAP) for small GTPase RAB22A, converting active RAB22A-GTP to the inactive form RAB22A-GDP . Plays a role in endocytosis and intracellular protein transport. Recruited by ANK2 to phosphatidylinositol 3-phosphate (PI3P)-positive early endosomes, where it inactivates RAB22A, and promotes polarized trafficking to the leading edge of the migrating cells. Part of the ANK2/RABGAP1L complex which is required for the polarized recycling of fibronectin receptor ITGA5 ITGB1 to the plasma membrane that enables continuous directional cell migration (By similarity). .
Accessions	ENST00000635248.1 ENST00000478442.5 [Q5R372-9] A0A0U1RQX4 ENST00000465412.5 ENST00000367688.3 [B7ZAP0-1] ENST00000486220.5 [Q5R372-9] ENST00000529145.6 B7ZAP0 ENST00000251507.8 [Q5R372-1] A0A0U1RQY6 A0A0C4DG54 ENST00000392064.6 A0A0U1RQT5 ENST00000485114.1 ENST00000469553.6 F5H8L0 ENST00000681986.1 A0A0U1RQV7 ENST00000489615.5 [Q5R372-8] ENST00000457696.1 ENST00000325589.9 [Q5R372-7] ENST00000474375.6 A0A0U1RRM5 A0A804HKD7 ENST00000347255.6 [Q5R372-5] Q5R372 ENST00000357444.10 [Q5R372-2] E9PNV2 E9PS63 ENST00000367690.5 ENST00000367687.5 [Q5R372-6]

GO_0015031	Biological process	protein transport
GO_0032880	Biological process	regulation of protein localization
GO_0043087	Biological process	regulation of GTPase activity
GO_0006897	Biological process	endocytosis
GO_0005794	Cellular component	Golgi apparatus
GO_0005769	Cellular component	early endosome
GO_0005634	Cellular component	nucleus
GO_0031267	Molecular function	small GTPase binding
GO_0005096	Molecular function	GTPase activator activity

RABGAP1L report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review