RAB32 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035646Biological processendosome to melanosome transport
GO_0090382Biological processphagosome maturation
GO_0006886Biological processintracellular protein transport
GO_0032438Biological processmelanosome organization
GO_0016192Biological processvesicle-mediated transport
GO_0007005Biological processmitochondrion organization
GO_0019882Biological processantigen processing and presentation
GO_0072657Biological processprotein localization to membrane
GO_1903232Biological processmelanosome assembly
GO_0012505Cellular componentendomembrane system
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0005769Cellular componentearly endosome
GO_0005802Cellular componenttrans-Golgi network
GO_0033162Cellular componentmelanosome membrane
GO_0044233Cellular componentmitochondria-associated endoplasmic reticulum membrane contact site
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0045335Cellular componentphagocytic vesicle
GO_0031905Cellular componentearly endosome lumen
GO_0030670Cellular componentphagocytic vesicle membrane
GO_0005741Cellular componentmitochondrial outer membrane
GO_0042470Cellular componentmelanosome
GO_0035612Molecular functionAP-2 adaptor complex binding
GO_0030742Molecular functionGTP-dependent protein binding
GO_0035651Molecular functionAP-3 adaptor complex binding
GO_0005525Molecular functionGTP binding
GO_0036461Molecular functionBLOC-2 complex binding
GO_0035650Molecular functionAP-1 adaptor complex binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAB32
Protein nameRas-related protein Rab-32
Synonyms
DescriptionFUNCTION: Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission . Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis . Plays an important role in the control of melanin production and melanosome biogenesis . In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity). .

AccessionsQ13637
ENST00000367495.4