LIPG | OmnibusX

Name	Number of supported studies	Average coverage
retinal cone cell	5 studies	20% ± 3%	Explore
retinal pigment epithelial cell	3 studies	20% ± 4%	Explore
hepatocyte	3 studies	42% ± 16%	Explore
brush cell	3 studies	53% ± 12%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of LIPG at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	28346.15	653 / 653	87%	65.27	527 / 605
liver	100%	6381.48	226 / 226	78%	7.93	318 / 406
intestine	79%	738.33	767 / 966	92%	9.47	486 / 527
lung	90%	1900.84	522 / 578	54%	3.61	625 / 1155
stomach	53%	347.90	192 / 359	90%	9.03	258 / 286
kidney	100%	1906.45	89 / 89	41%	3.08	365 / 901
pancreas	34%	138.14	112 / 328	84%	5.34	150 / 178
bladder	38%	474.57	8 / 21	71%	7.93	358 / 504
esophagus	32%	185.23	458 / 1445	74%	6.58	136 / 183
ureter	0%	0	0 / 0	100%	2.91	1 / 1
brain	38%	195.15	993 / 2642	59%	3.54	419 / 705
prostate	53%	328.48	129 / 245	9%	0.44	46 / 502
uterus	9%	32.34	16 / 170	49%	3.89	225 / 459
skin	49%	235.35	894 / 1809	8%	0.32	38 / 472
breast	34%	239.39	155 / 459	14%	1.12	160 / 1118
adipose	41%	408.75	495 / 1204	0%	0	0 / 0
muscle	39%	304.54	311 / 803	0%	0	0 / 0
ovary	12%	35.83	21 / 180	23%	0.99	100 / 430
lymph node	0%	0	0 / 0	34%	1.31	10 / 29
tonsil	0%	0	0 / 0	22%	1.31	10 / 45
heart	22%	176.65	187 / 861	0%	0	0 / 0
blood vessel	19%	111.26	248 / 1335	0%	0	0 / 0
adrenal gland	9%	30.47	23 / 258	8%	0.50	19 / 230
peripheral blood	10%	49.91	95 / 929	0%	0	0 / 0
spleen	5%	17.40	11 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007584	Biological process	response to nutrient
GO_0055091	Biological process	phospholipid homeostasis
GO_0010983	Biological process	positive regulation of high-density lipoprotein particle clearance
GO_0043691	Biological process	reverse cholesterol transport
GO_0034375	Biological process	high-density lipoprotein particle remodeling
GO_0032376	Biological process	positive regulation of cholesterol transport
GO_0019433	Biological process	triglyceride catabolic process
GO_0006633	Biological process	fatty acid biosynthetic process
GO_0006629	Biological process	lipid metabolic process
GO_0050746	Biological process	regulation of lipoprotein metabolic process
GO_0042632	Biological process	cholesterol homeostasis
GO_0009395	Biological process	phospholipid catabolic process
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0005769	Cellular component	early endosome
GO_0005794	Cellular component	Golgi apparatus
GO_0009986	Cellular component	cell surface
GO_0008201	Molecular function	heparin binding
GO_0004620	Molecular function	phospholipase activity
GO_0008970	Molecular function	phospholipase A1 activity
GO_0004465	Molecular function	lipoprotein lipase activity
GO_0052739	Molecular function	phosphatidylserine 1-acylhydrolase activity
GO_0052740	Molecular function	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GO_0004806	Molecular function	triglyceride lipase activity

Gene name	LIPG
Protein name	Endothelial lipase (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL) (Phospholipase A1) (EC 3.1.1.32) Lipase G, endothelial type phospholipase A1 (EC 3.1.1.32) (Phospholipase A1) Phospholipase A1
Synonyms	UNQ387/PRO719
Description	FUNCTION: Exerts both phospholipase and triglyceride lipase activities . More active as a phospholipase than a triglyceride lipase . Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates . Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins . .
Accessions	Q9Y5X9 B4DTR8 ENST00000579750.1 ENST00000577628.5 ENST00000580036.5 [Q9Y5X9-2] J3QQQ0 J3KTN7 ENST00000427224.6 ENST00000261292.9 [Q9Y5X9-1] ENST00000583083.1 A0A075B751

LIPG report