Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 10 studies | 44% ± 17% | |
glutamatergic neuron | 7 studies | 49% ± 28% | |
microglial cell | 7 studies | 34% ± 13% | |
oligodendrocyte | 7 studies | 53% ± 13% | |
endothelial cell | 7 studies | 28% ± 10% | |
GABAergic neuron | 6 studies | 51% ± 25% | |
oligodendrocyte precursor cell | 6 studies | 43% ± 17% | |
macrophage | 5 studies | 29% ± 18% | |
myeloid cell | 4 studies | 34% ± 21% | |
epithelial cell | 4 studies | 29% ± 10% | |
fibroblast | 4 studies | 36% ± 16% | |
Mueller cell | 4 studies | 40% ± 15% | |
amacrine cell | 4 studies | 32% ± 10% | |
retinal cone cell | 4 studies | 60% ± 20% | |
retinal rod cell | 4 studies | 61% ± 14% | |
smooth muscle cell | 4 studies | 31% ± 5% | |
pericyte | 4 studies | 28% ± 12% | |
interneuron | 4 studies | 64% ± 22% | |
classical monocyte | 3 studies | 18% ± 2% | |
adipocyte | 3 studies | 40% ± 19% | |
GABAergic amacrine cell | 3 studies | 45% ± 9% | |
glycinergic amacrine cell | 3 studies | 35% ± 5% | |
retina horizontal cell | 3 studies | 27% ± 5% | |
retinal ganglion cell | 3 studies | 29% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 181.29 | 180 / 180 | 99% | 3.11 | 425 / 430 |
prostate | 100% | 155.62 | 245 / 245 | 99% | 3.05 | 496 / 502 |
esophagus | 100% | 195.55 | 1441 / 1445 | 95% | 2.28 | 173 / 183 |
brain | 94% | 108.25 | 2485 / 2642 | 98% | 2.54 | 693 / 705 |
thymus | 100% | 181.41 | 653 / 653 | 92% | 1.93 | 556 / 605 |
skin | 100% | 306.17 | 1809 / 1809 | 86% | 1.86 | 405 / 472 |
lung | 99% | 170.82 | 575 / 578 | 83% | 1.59 | 956 / 1155 |
bladder | 100% | 201.48 | 21 / 21 | 81% | 1.55 | 410 / 504 |
uterus | 100% | 168.52 | 170 / 170 | 80% | 1.52 | 367 / 459 |
pancreas | 100% | 96.97 | 327 / 328 | 79% | 1.39 | 140 / 178 |
stomach | 99% | 137.00 | 357 / 359 | 77% | 1.44 | 221 / 286 |
adrenal gland | 100% | 192.30 | 258 / 258 | 76% | 1.35 | 175 / 230 |
breast | 100% | 176.94 | 459 / 459 | 73% | 1.25 | 811 / 1118 |
kidney | 98% | 89.45 | 87 / 89 | 69% | 1.34 | 626 / 901 |
intestine | 100% | 158.90 | 966 / 966 | 64% | 1.04 | 337 / 527 |
liver | 75% | 45.35 | 169 / 226 | 64% | 1.11 | 259 / 406 |
adipose | 100% | 206.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 208.18 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 113.27 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.00 | 1 / 1 |
muscle | 99% | 90.59 | 795 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 279.13 | 916 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 2.46 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 91% | 1.83 | 73 / 80 |
heart | 85% | 68.36 | 734 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 47% | 0.74 | 21 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0043305 | Biological process | negative regulation of mast cell degranulation |
GO_0038109 | Biological process | Kit signaling pathway |
GO_0002686 | Biological process | negative regulation of leukocyte migration |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_0097531 | Biological process | mast cell migration |
GO_0032715 | Biological process | negative regulation of interleukin-6 production |
GO_0060368 | Biological process | regulation of Fc receptor mediated stimulatory signaling pathway |
GO_0006612 | Biological process | protein targeting to membrane |
GO_1900235 | Biological process | negative regulation of Kit signaling pathway |
GO_0046580 | Biological process | negative regulation of Ras protein signal transduction |
GO_0043303 | Biological process | mast cell degranulation |
GO_0001933 | Biological process | negative regulation of protein phosphorylation |
GO_0032764 | Biological process | negative regulation of mast cell cytokine production |
GO_0050728 | Biological process | negative regulation of inflammatory response |
GO_0098935 | Biological process | dendritic transport |
GO_0048261 | Biological process | negative regulation of receptor-mediated endocytosis |
GO_0015031 | Biological process | protein transport |
GO_0033004 | Biological process | negative regulation of mast cell activation |
GO_0005730 | Cellular component | nucleolus |
GO_0030139 | Cellular component | endocytic vesicle |
GO_0055037 | Cellular component | recycling endosome |
GO_0005769 | Cellular component | early endosome |
GO_0031901 | Cellular component | early endosome membrane |
GO_0030425 | Cellular component | dendrite |
GO_0005829 | Cellular component | cytosol |
GO_0003677 | Molecular function | DNA binding |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0031267 | Molecular function | small GTPase binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | RABGEF1 |
Protein name | RAB guanine nucleotide exchange factor 1 Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) |
Synonyms | RABEX5 |
Description | FUNCTION: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By similarity). . |
Accessions | V9GYI8 ENST00000442563.5 ENST00000450873.6 [Q9UJ41-2] ENST00000439720.3 Q9UJ41 A0A1W2PPY0 ENST00000484547.7 E9PFK9 ENST00000284957.9 [Q9UJ41-2] ENST00000607882.5 C9JDA2 |