WASH4P report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of WASH4P at tissue level.

III. Associated gene sets

GO_0042147Biological processretrograde transport, endosome to Golgi
GO_0034314Biological processArp2/3 complex-mediated actin nucleation
GO_0016197Biological processendosomal transport
GO_0006887Biological processexocytosis
GO_0034315Biological processregulation of Arp2/3 complex-mediated actin nucleation
GO_0032456Biological processendocytic recycling
GO_0031901Cellular componentearly endosome membrane
GO_0055038Cellular componentrecycling endosome membrane
GO_0071203Cellular componentWASH complex
GO_0005829Cellular componentcytosol
GO_0055037Cellular componentrecycling endosome
GO_0005769Cellular componentearly endosome
GO_0043015Molecular functiongamma-tubulin binding
GO_0043014Molecular functionalpha-tubulin binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameWASH4P
Protein namePutative WAS protein family homolog 4 (Protein FAM39CP)
SynonymsFAM39CP
DescriptionFUNCTION: May act as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. .

AccessionsA8MWX3