Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 33% ± 19% | |
endothelial cell | 3 studies | 28% ± 13% |
Insufficient scRNA-seq data for expression of WASH4P at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 85.67 | 170 / 170 | 89% | 2.10 | 410 / 459 |
brain | 99% | 54.94 | 2605 / 2642 | 88% | 1.73 | 619 / 705 |
thymus | 100% | 84.84 | 653 / 653 | 84% | 1.78 | 508 / 605 |
skin | 99% | 65.58 | 1793 / 1809 | 83% | 1.53 | 390 / 472 |
prostate | 100% | 96.84 | 245 / 245 | 82% | 1.50 | 410 / 502 |
kidney | 100% | 76.35 | 89 / 89 | 82% | 1.59 | 735 / 901 |
bladder | 100% | 65.14 | 21 / 21 | 80% | 1.90 | 401 / 504 |
breast | 100% | 69.63 | 459 / 459 | 79% | 1.55 | 888 / 1118 |
pancreas | 99% | 43.65 | 324 / 328 | 74% | 1.36 | 132 / 178 |
lung | 100% | 63.22 | 576 / 578 | 70% | 1.36 | 807 / 1155 |
adrenal gland | 100% | 56.57 | 258 / 258 | 68% | 1.15 | 156 / 230 |
liver | 99% | 34.50 | 224 / 226 | 55% | 1.06 | 225 / 406 |
intestine | 100% | 76.11 | 965 / 966 | 42% | 0.74 | 220 / 527 |
stomach | 100% | 50.28 | 359 / 359 | 27% | 0.50 | 76 / 286 |
ovary | 100% | 75.02 | 180 / 180 | 13% | 0.20 | 56 / 430 |
esophagus | 100% | 60.68 | 1445 / 1445 | 4% | 0.07 | 8 / 183 |
spleen | 100% | 109.22 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.19 | 1 / 1 |
blood vessel | 100% | 56.89 | 1330 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 60.76 | 1198 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 56.69 | 922 / 929 | 0% | 0 | 0 / 0 |
muscle | 99% | 50.49 | 794 / 803 | 0% | 0 | 0 / 0 |
heart | 95% | 34.73 | 820 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 89% | 1.49 | 71 / 80 |
lymph node | 0% | 0 | 0 / 0 | 86% | 2.39 | 25 / 29 |
tonsil | 0% | 0 | 0 / 0 | 71% | 1.28 | 32 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
GO_0034314 | Biological process | Arp2/3 complex-mediated actin nucleation |
GO_0016197 | Biological process | endosomal transport |
GO_0006887 | Biological process | exocytosis |
GO_0034315 | Biological process | regulation of Arp2/3 complex-mediated actin nucleation |
GO_0032456 | Biological process | endocytic recycling |
GO_0031901 | Cellular component | early endosome membrane |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0071203 | Cellular component | WASH complex |
GO_0005829 | Cellular component | cytosol |
GO_0055037 | Cellular component | recycling endosome |
GO_0005769 | Cellular component | early endosome |
GO_0043015 | Molecular function | gamma-tubulin binding |
GO_0043014 | Molecular function | alpha-tubulin binding |
GO_0003779 | Molecular function | actin binding |
Gene name | WASH4P |
Protein name | Putative WAS protein family homolog 4 (Protein FAM39CP) |
Synonyms | FAM39CP |
Description | FUNCTION: May act as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. . |
Accessions | A8MWX3 |